Hemagglutination and intestinal adherence properties of clinical and environmental isolates of non-O1 Vibrio cholerae
Hemagglutination and intestinal adherence properties of clinical and environmental isolates of non-O1 Vibrio cholerae
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非 O1 霍乱弧菌临床和环境分离株的血凝和肠道粘附特性
DOI：
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发表时间：
1989
影响因子：
4.4
通讯作者：
A. C. Ghose
中科院分区：
文献类型：
--
作者：
K. Datta;C. Dasgupta;A. C. Ghose
研究了非o1型霍乱弧菌的体外血凝和肠道粘附特性。细胞相关血凝素滴度与肠道黏附指数之间没有明确的相关性。糖和糖蛋白介导的抑制数据也表明，在受体结构方面，血凝和粘附过程之间存在差异。n -乙酰d -氨基葡萄糖能不同程度地抑制大多数霍乱弧菌的肠道粘附。这一观察结果为这些生物的生态行为提供了一个可能的解释，这些生物已知与浮游动物表面的几丁质（几丁质：n -乙酰基d -氨基葡萄糖的均聚物）有关。临床分离的肠道粘附指数和环境分离的肠道粘附指数之间没有任何显著差异，这表明肠道粘附可能是这些微生物定植和随后表达致病性的必要条件，但不是充分条件。
Hemagglutination and intestinal adherence properties of non-O1 Vibrio cholerae were studied in vitro. No definite correlation between the cell-associated hemagglutinin titers and the intestinal adhesion indices was noted. Sugar- and glycoprotein-mediated inhibition data also indicated differences between the hemagglutination and adherence processes in respect to the receptor structures. Intestinal adherence of most V. cholerae strains could be inhibited to various extents by N-acetyl D-glucosamine. This observation provides a likely explanation for the ecological behavior of these organisms, which are known to associate themselves with chitinous (chitin:homopolymer of N-acetyl D-glucosamine) surfaces of zooplankton. The absence of any significant difference between the intestinal adherence indices of clinical and environmental isolates suggests that intestinal adhesion may be an essential but not sufficient prerequisite for colonization by and subsequent expression of pathogenicity of these microorganisms.
与非 O1 霍乱弧菌临床分离株相关的毒力机制。
DOI：
10.1016/s0176-6724(86)80040-2
发表时间：
1986
期刊：
Zentralblatt fur Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology
影响因子：
--
作者：
Shehabi,AA;Drexler,H;Richardson,SH
通讯作者：
Richardson,SH