The BCG story: lessons from the past and implications for the future.
The BCG story: lessons from the past and implications for the future.
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BCG 故事：过去的教训和对未来的影响。
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
P. Fine
中科院分区：
文献类型：
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作者：
P. Fine
BCG (bacille Calmette-Guérin) vaccines are at once among the least satisfactory and yet the most widely used of all vaccines today. Their variable efficacy against tuberculosis and leprosy is still not understood and points to a fundamental unsolved problem in vaccine immunology. The extensive use of BCG vaccines means that there are few BCG-free populations in the world that would be suitable for trials of future antimycobacterial vaccines. These facts have implications with regard to strategies for the development and testing of new vaccines against mycobacterial diseases.
