Dynamic particle enhancement in limited-view optoacoustic tomography

Dynamic particle enhancement in limited-view optoacoustic tomography
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DOI:
10.1364/ol.42.000827
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发表时间:
2017-02-15
期刊:
影响因子:
3.6
通讯作者:
Razansky, Daniel
Razansky, Daniel
中科院分区:
物理与天体物理2区
文献类型:
--
作者:
Dean-Ben, X. Luis;Ding, Lu;Razansky, Daniel

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有限视角伪影通常存在于光声层析成像图像中,主要是由于成像系统施加的实际几何和物理约束。本文提出了一种动态粒子增强光声层析成像(DPOT)方法,用于改善有限视野下光声图像的对比度和可见度。该方法是基于一个时间序列的层析重建表示稀疏分布的运动粒子的非线性组合。我们通过对悬浮微球在三维空间中的流动进行动态成像来展示实验性能,这显示了DPOT在活体血管造影成像中的应用前景。(C)2017美国光学学会
Limited-view artifacts are commonly present in optoacoustic tomography images, mainly due to practical geometrical and physical constraints imposed by the imaging systems. Herein, a new approach called dynamic particle-enhanced optoacous-tic tomography (DPOT) is proposed for improving image contrast and visibility of optoacoustic images under lim-ited- view scenarios. The method is based on a nonlinear combination of a temporal sequence of tomographic recon-structions representing sparsely distributed moving particles. We demonstrate experimental performance by dynamically imaging the flow of suspended microspheres in three dimen-sions, which shows promise for DPOT applicability in angio-graphic imaging in living organisms. (C) 2017 Optical Society of America