Isolation of West Nile virus from mosquitoes, crows, and a Cooper's hawk in Connecticut
Isolation of West Nile virus from mosquitoes, crows, and a Cooper's hawk in Connecticut
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DOI：
10.1126/science.286.5448.2331
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发表时间：
1999-12-17
期刊：
影响因子：
56.9
通讯作者：
Van Kruiningen, HJ
中科院分区：
文献类型：
--
作者：
Anderson, JF;Andreadis, TG;Van Kruiningen, HJ
西尼罗河（WN）病毒，一种原产于非洲的由蚊子传播的病毒。亚洲。从康涅狄格州的两种蚊子（淡色库蚊和伊蚊）以及 28 只美洲乌鸦（Corvus brachyrhynchos）和一只库珀鹰（Accipiter cooperii）的脑组织中分离得到。通过比较系统发育分析对来自四种不同宿主的病毒分离株的部分基因组进行了测序和分析。我们来自康涅狄格州的分离株彼此相似，并且与来自罗马尼亚的两种 WN 分离株关系最为密切（差异分别为 2.8% 和 3.6%）。如果在北美建立，WN 病毒可能会对人类健康和鸟类健康产生严重影响。
West Nile (WN) virus, a mosquito-transmitted virus native to Africa. Asia. and Europe, was isolated from two species of mosquitoes, Culex pipiens and Aedes vexans, and from brain tissues of 28 American crows, Corvus brachyrhynchos, and one Cooper's hawk, Accipiter cooperii, in Connecticut. A portion of the genome of virus isolates from four different hosts was sequenced and analyzed by comparative phylogenetic analysis. Our isolates from Connecticut were similar to one another and most closely related to two WN isolates from Romania (2.8 and 3.6 percent difference). If established in North America, WN virus will likely have severe effects on human health and on the health of populations of birds.