Highly regioselective syntheses of substituted triphenylenes from 1,2,4-trisubstituted arenes via a co-catalyzed intermolecular alkyne cyclotrimerization.
Highly regioselective syntheses of substituted triphenylenes from 1,2,4-trisubstituted arenes via a co-catalyzed intermolecular alkyne cyclotrimerization.
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DOI：
10.1021/jo400570b
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发表时间：
2013-05
期刊：
影响因子：
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通讯作者：
Ling Xu;Ruocheng Yu;Yuefan Wang;Jia-Hua Chen;Zhen Yang
中科院分区：
文献类型：
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作者：
Ling Xu;Ruocheng Yu;Yuefan Wang;Jia-Hua Chen;Zhen Yang
在此，我们报告了一种新的方法的发展，用于从相应的1，2，4-三取代的芳烃，这本身产生的高度区域选择性的方式根据分子间的炔环三聚反应，催化的一种新的Co-TMTU配合物的合成取代的三苯基。这种高度区域选择性的反应形成的1，2，4-三取代芳烃将是一个有价值的除了过多的工具已经提供给合成化学家，并鼓励进一步的机制研究，这一重要的炔三聚过程。
Herein, we report the development of a new method for the syntheses of substituted triphenylenes from the corresponding 1,2,4-trisubstituted arenes, which were themselves generated in a highly regioselective manner according to an intermolecular alkyne cyclotrimerization reaction that was catalyzed by a novel Co-TMTU complex. This highly regioselective reaction for the formation of 1,2,4-trisubstituted arenes will be a valuable addition to the plethora of tools already available to synthetic chemists and encourage further mechanistic studies of this important alkyne trimerization process.