AIN-76 diet: should we change the formulation?
AIN-76 diet: should we change the formulation?
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AIN-76饮食：我们应该改变配方吗？
DOI：
10.1093/jn/119.8.1081
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
P. G. Reeves
中科院分区：
文献类型：
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作者：
P. G. Reeves
这是 AIN-76 研讨会的摘要，该研讨会于 1989 年 3 月 19 日在路易斯安那州新奥尔良举行的 FASEB 会议上举行。这次初步研讨会的目的是讨论是否应该对 AIN-76 啮齿动物饮食的配方进行改变。以下是各个专家委员会提出的一些建议的要点，但它们并不构成啮齿动物饮食的新制定：1）脂肪含量应不少于饮食重量的10％，并且脂肪酸含量应标准化； 2）纤维素纤维的来源应该有一定的标准化，无定型优于结晶型； 3）如果膳食脂肪含量增加到10%，膳食维生素E水平应提高50%； 4) 一种建议的降低长期食用 AIN-76 饮食的大鼠肾钙质沉着症发生率的替代方案是将磷酸氢钙含量降低至 400 g/kg 矿物质混合物； 5) 锰含量应降至 10 mg/kg 饮食。
This is a summary of the AIN-76 Workshop held on March 19, 1989, at the FASEB meetings in New Orleans, LA. The purpose of this preliminary workshop was to discuss whether or not changes should be made in the formulation of the AIN-76 rodent diet. The following are highlights of some of the recommendations made by various expert committees, but they do not constitute a new formulation of the rodent diet: 1) fat should comprise no less than 10% by weight of the diet, and the fatty acid content should be standardized; 2) there should be some standardization of the source of cellulose fiber, and the amorphous form is better than the crystalline form; 3) the level of dietary vitamin E should be raised by 50% if the dietary fat content is increased to 10%; 4) one suggested alternative to decrease the incidence of nephrocalcinosis in rats consuming the AIN-76 diet for long periods is to decrease the calcium phosphate dibasic content to 400 g/kg mineral mixture; and 5) the level of manganese should be decreased to 10 mg/kg diet.