THE ELECTROENCEPHALOGRAM IN SEPSIS-ASSOCIATED ENCEPHALOPATHY

THE ELECTROENCEPHALOGRAM IN SEPSIS-ASSOCIATED ENCEPHALOPATHY
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DOI:
10.1097/00004691-199201000-00016
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发表时间:
1992-01-01
影响因子:
2.4
通讯作者:
WELLS, GA
WELLS, GA
中科院分区:
医学4区
文献类型:
--
作者:
YOUNG, GB;BOLTON, CF;WELLS, GA

文献摘要

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为了确定脓毒性脑病的脑电图和相关临床特征,我们研究了 62 名血培养呈阳性的患者。患者被分为三个临床组:非脑病(NE)、轻度脑病(ME)和重度脑病(SE);后两组有弥漫性脑功能障碍。脑电图分为五组:正常、过度θ、主要δ、三相波以及抑制或爆发抑制,按严重程度升序排列。脑电图 (1) 比我们的脑病临床标准更敏感,(2) 显示的特征,当考虑到临床和实验室特征时,与潜在可逆性脑病相一致,(3) 具有与死亡率百分比相关的明确类别,即使在单个临床组内也是如此。我们的结论是,脑电图是脓毒症脑病脑功能的敏感指标,在脓毒症患者的重症监护监测中特别有用。
To define the EEG and associated clinical features of septic encephalopathy, we studied 62 patients with positive blood cultures. Patients were divided into three clinical groups: nonencephalopathic (NE), mildly encephalopathic (ME), and severely encephalopathic (SE); the latter two groups had diffuse cerebral dysfunction. EEGs were classified into five groups: normal, excessive theta, predominant delta, triphasic waves, and suppression or burst suppression, in ascending order of severity. The EEG (1) was more sensitive than our clinical criteria for encephalopathy, (2) showed features that were, when considered with clinical and laboratory characteristics, compatible with a potentially reversible encephalopathy, and (3) had well-defined categories that correlated with percent mortality, even within a single clinical group. We conclude that the EEG is a sensitive index of brain function in septic encephalopathy and that it is especially useful in the intensive care monitoring of patients with sepsis.