Helicobacter pylori: microbiology of a 'slow' bacterial infection.
Helicobacter pylori: microbiology of a 'slow' bacterial infection.
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DOI：
10.1016/0966-842x(93)90047-u
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发表时间：
1993-10-01
影响因子：
15.9
通讯作者：
Blaser, M J
中科院分区：
文献类型：
--
作者：
Blaser, M J
幽门螺杆菌生活在人类的胃粘液层中，并诱导慢性炎症反应，可导致消化性溃疡和胃肿瘤。幽门螺杆菌感染可以被认为是一个“缓慢”的适应性和自动调节的过程。这种缓慢的细菌病原体存活并与宿主免疫系统相互作用的机制可能为其他持久性粘膜病原体提供模型。
The bacterium Helicobacter pylori lives in the gastric mucus layer of humans and induces a chronic inflammatory response that can result in both peptic ulceration and gastric neoplasms. Helicobacter pylori infection can be considered as a 'slow', adaptive and autoregulating process. The mechanisms by which this slow bacterial pathogen survives and interacts with the host immune system may provide a model for other persistent mucosal pathogens.