Reinterpreting the pressure-volume curve in patients with acute respiratory distress syndrome.
Reinterpreting the pressure-volume curve in patients with acute respiratory distress syndrome.
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DOI：
10.1097/00075198-200202000-00006
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发表时间：
2002-02-01
影响因子：
3.3
通讯作者：
Hickling, Keith G
中科院分区：
文献类型：
--
作者：
Hickling, Keith G
新的证据需要重新解释充气压力-容积曲线，并表明，无论是较低的或较高的拐点提供可靠的信息，以确定安全的呼吸机设置在急性呼吸窘迫综合征。肺复张可能在整个充气压力-容积曲线中持续进行，可能需要研究放气压力-容积曲线、部分放气后的再充气或肺复张操作后的呼气末正压递减试验，以确定开肺呼气末正压。
New evidence requires a reinterpretation of the inflation pressure-volume curve and suggests that neither the lower nor the upper inflection point provides reliable information to determine safe ventilator settings in the acute respiratory distress syndrome. Recruitment probably continues throughout the inflation pressure-volume curve, and studies of the deflation pressure-volume curve, reinflations after partial deflation, or decremental positive end-expiratory pressure trials after a recruitment maneuver are probably needed to determine open-lung positive end-expiratory pressure.