Social and psychological contributions to the co-occurrence of sub-threshold psychotic experiences and suicidal behavior

Social and psychological contributions to the co-occurrence of sub-threshold psychotic experiences and suicidal behavior
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DOI:
10.1007/s00127-015-1139-6
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发表时间:
2015-12-01
影响因子:
4.4
通讯作者:
Hilimire, Matthew R.
Hilimire, Matthew R.
中科院分区:
医学2区
文献类型:
--
作者:
DeVylder, Jordan E.;Jahn, Danielle R.;Hilimire, Matthew R.

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精神病经历和自杀行为通常在一般人群中同时发生,这可能对自杀预防方法产生影响。然而,很少有人知道这种关系在非临床样本的性质。这项横断面研究旨在通过检验精神病经历与自杀相关结局之间的关系,年轻的成年大学生(N = 590)被评估的精神病经历,自杀行为,以及通过回顾过去的流行病学研究和荟萃分析选择的一套全面的24个潜在的共同风险因素。非参数自举回归模型被用来检验这些因素是否减弱或消除了精神病经历和自杀相关结局之间的关联。精神病经历与自杀意念和行为的风险更大相关。调整心理社会因素,特别是那些有助于累积的压力,占精神病的经验和自杀相关的结果之间的关联,除了广义定义的自杀ideation.These结果表明,在过去的研究中表现出的精神病的经验和自杀行为之间的强大的关联可能主要是由共同的风险因素,而不是因果关系。在我们的样本中,自杀行为和阈下精神病似乎是跨诊断的临床结果,它们有共同的原因,特别是累积的压力,但彼此之间没有因果关系。
Psychotic experiences and suicidal behavior commonly co-occur in the general population, which can have implications for suicide prevention approaches. However, little is known about the nature of this relation in non-clinical samples. This cross-sectional study aimed to address a research gap by testing whether the relation between psychotic experiences and suicide-related outcomes (ideation, intent, and attempts) is explained by common social and psychological factors.Young adult college students (N = 590) were assessed for psychotic experiences, suicidal behavior, and a comprehensive set of 24 potential shared risk factors selected through review of past epidemiological studies and meta-analyses. Nonparametric bootstrapped regression models were used to examine whether these factors attenuated or eliminated the associations between psychotic experiences and suicide-related outcomes.Psychotic experiences were associated with greater risk for suicidal ideation and behaviors. Adjustment for psychosocial factors, particularly those contributing to cumulative stress, accounted for the associations between psychotic experiences and suicide-related outcomes, except broadly defined suicidal ideation.These results suggest that the robust associations between psychotic experiences and suicidal behavior demonstrated in past studies may be primarily explained by shared risk factors, rather than by causal relations. In our sample, suicidal behavior and sub-threshold psychosis appear to be trans diagnostic clinical outcomes that share common causes, notably cumulative stress, but do not cause one another.