Guidelines for the treatment of skin and mucosal lesions in Behcet's disease: A secondary publication

Guidelines for the treatment of skin and mucosal lesions in Behcet's disease: A secondary publication
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DOI:
10.1111/1346-8138.15207
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发表时间:
2020-01-06
影响因子:
3.1
通讯作者:
Kaneko,Fumio
Kaneko,Fumio
中科院分区:
医学4区
文献类型:
--
作者:
Nakamura,Koichiro;Iwata,Yohei;Kaneko,Fumio

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在本研究中,我们提出了白塞氏病皮肤粘膜病变的诊断和治疗指南,白塞氏病是一种慢性炎症性疾病,其特征是累及多个器官,包括皮肤粘膜、眼、血管、肠道和中枢神经系统病变。它经常出现在中东地中海至东亚地区。皮肤表现包括结节性红斑、丘疹脓疱性病变和血栓性静脉炎,粘膜表现包括口腔和生殖器溃疡。这些皮肤粘膜病变是白塞病的最初症状,对于该病的早期诊断非常重要。此外,这些表现也会在疾病的长期病程中反复出现并持续存在。皮肤粘膜病变的治疗对于预防复发很重要。我们制定了共识指南,为全科医生、皮肤科医生和医生提供有关白塞病皮肤粘膜病变治疗的建议。
In the current study, we present guidelines for the diagnosis and treatment of the mucocutaneous lesions of Behçet's disease, which is a chronic inflammatory disease characterized by the involvement of various organs, including mucocutaneous, ocular, vascular, intestinal and central nervous system lesions. It is often identified in the Middle East Mediterranean to East Asia region. Skin manifestations include erythema nodosum, papulopustular lesions and thrombophlebitis, and mucosal manifestations include oral and genital ulcers. These mucocutaneous lesions are characteristically the first signs of Behçet's disease and are important to be recognized for the early diagnosis of the disease. Moreover, these manifestations also recur and persist over the long‐term course of the disease. The management of mucocutaneous lesions is important to prevent recurrence. We developed consensus guidelines that provide recommendations for general practitioners and dermatologists and physicians on the management of the mucocutaneous lesions of Behçet's disease.