Glycobiology of Host‐Microbe Interactions in the Gut
Glycobiology of Host‐Microbe Interactions in the Gut
复制标题
肠道宿主-微生物相互作用的糖生物学
DOI：
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发表时间：
2019
期刊：
影响因子：
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通讯作者：
N. Juge
中科院分区：
文献类型：
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作者：
N. Juge
胃肠道(GI)由数万亿种细菌定居，这些细菌统称为“肠道微生物区系”，对人类健康有深远影响。细菌黏附是寄主定植的关键步骤。细胞表面蛋白(粘附素或凝集素)通过与宿主蛋白或糖结合物相互作用，介导与宿主的附着并启动定植。然而，与病原体相反，共生细菌或益生菌与肠道粘连的分子基础仍然不清楚。
The gastrointestinal (GI) tract is colonised by trillions of bacteria collectively known as the ‘gut microbiota’ which have a profound impact on human health. Bacterial adhesion is a critical step for colonization of the host. Cell surface proteins (adhesins or lectins) mediate attachment to the host and initiate colonization by interacting with host proteins or glycoconjugates. However, in contrast to pathogens, the molecular basis for adhesion of commensal bacteria or probiotics to the gut remain poorly defined.
影响因子：
5.1
作者：
Etzold, Sabrina;Kober, Olivia I.;Juge, Nathalie
通讯作者：
Juge, Nathalie