Malignant fibrous histiocytoma. A clinicopathologic study of 130 cases.
Malignant fibrous histiocytoma. A clinicopathologic study of 130 cases.
复制标题
恶性纤维组织细胞瘤。
DOI：
--
复制
发表时间：
1980
期刊：
影响因子：
--
通讯作者：
H. Iwasaki
中科院分区：
文献类型：
--
作者：
M. Enjoji;H. Hashimoto;M. Tsuneyoshi;H. Iwasaki
报告130例软组织恶性纤维组织细胞瘤的临床病理分析。这种恶性肿瘤主要发生在中晚期成人，最常发生在四肢近端（48%），包括大腿和臀部（35%）。MFH可分为普通型（故事状和多形性）、粘液型、黄色肉芽肿型和巨细胞型，普通型占100例（77%）。故事状和粘液样肿瘤的预后较多形性和其他类型的肿瘤好，总的相对5年生存率为48%。肿瘤的深度也影响预后，深度肿瘤的生存率显著降低。肿瘤局部复发率为48%。由于资料不全，仅26例患者证实转移，且最常见于肺（73%）。此外，在有限的情况下，电镜，组织化学和组织培养的结果，关于组织发生的MFH。
A clinicopathologic study of 130 cases of malignant fibrous histiocytoma (MFH) of the soft tissues is reported. This malignant neoplasm principally of middle and late adults occurred most often in the proximal portions of the extremities (48%) including the thigh and buttocks (35%). MFH may be subclassified into common (storiform and pleomorphic), myxoid, xanthogranulomatous, and giant cell types, the common type being accounted for 100 cases (77%) of the series. The prognosis was more favorable in patients with storiform and myxoid tumors than in patients with pleomorphic or other type tumors, the overall relative five-year survival rate being 48%. The depth of the tumor also affected prognosis with a significantly lower survival rate in deeply situated tumors. The rate of local recurrence of the tumor was 48%. Because of incomplete informations, metastasis was confirmed in only 26 patients and was most frequently to the lung (73%). In addition, electron microscopic, histochemical and tissue culture findings in limited cases are presented, concerning the histogenesis of the MFH.