An autistic dimension - A proposed subtype of obsessive-compulsive disorder
An autistic dimension - A proposed subtype of obsessive-compulsive disorder
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DOI：
10.1177/1362361307075699
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发表时间：
2007-03-01
期刊：
影响因子：
5.2
通讯作者：
Bejerot, Susanne
中科院分区：
文献类型：
--
作者：
Bejerot, Susanne
本文关注自闭症谱系障碍（ASD：阿斯伯格综合征、自闭症和非典型自闭症）较轻微的形式可能在相当比例的强迫症（OCD）患者中具有临床重要性这一可能性，并基于这一观点讨论强迫症的亚型。该假设源于对强迫症和自闭症谱系障碍的丰富临床经验以及在医学文献数据库（MEDLINE）中的文献检索。神经心理缺陷在强迫症中比在惊恐障碍和抑郁症中更为常见。此外，强迫型和分裂型人格障碍在强迫症中过多出现。这些可能构成了自闭症谱系障碍被误解的临床表现。再者，重复行为和囤积在阿斯伯格综合征中很常见。有人提出，共病会导致一种更严重且对治疗有抵抗性的强迫症形式。伴有共病自闭症谱系障碍的强迫症应被视为一种有效的强迫症亚型，类似于伴有共病抽动的强迫症。一种奇特的人格，具有偏执、分裂型、回避型或强迫型特征，可能表明强迫症患者存在这些自闭症方面的特征。
This article focuses on the possibility that autism spectrum disorder (ASD: Asperger syndrome, autism and atypical autism) in its milder forms may be clinically important among a substantial proportion of patients with obsessive-compulsive disorder (OCD), and discusses OCD subtypes based on this proposition. The hypothesis derives from extensive clinical experience of OCD and ASD, and literature searches on MEDLINE. Neuropsychological deficits are more common in OCD than in panic disorder and depression. Moreover, obsessive-compulsive and schizotypal personality disorders are overrepresented in OCD. These may constitute misperceived clinical manifestations of ASD. Furthermore, repetitive behaviours and hoarding are common in Asperger syndrome. It is suggested that the comorbidity results in a more severe and treatment resistant form of OCD. OCD with comorbid ASD should be recognized as a valid OCD subtype, analogous to OCD with comorbid tics. An odd personality, with paranoid, schizotypal, avoidant or obsessive-compulsive traits, may indicate these autistic dimensions in OCD patients.