Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk
Effect of Allopurinol in Chronic Kidney Disease Progression and Cardiovascular Risk
复制标题
DOI：
10.2215/cjn.01580210
复制
发表时间：
2010-08-01
影响因子：
9.8
通讯作者：
Luno, Jose
中科院分区：
文献类型：
--
作者：
Goicoechea, Marian;Garcia de Vinuesa, Soledad;Luno, Jose
背景和目的：高尿酸血症与高血压、炎症、肾脏疾病进展和心血管疾病有关。然而，没有关于别嘌呤醇在慢性肾脏病患者中的作用的数据。设计，设置，参与者和测量：我们对113例估计GFR（eGFR）的患者进行了一项前瞻性，随机试验。
Background and objectives: Hyperuricemia is associated with hypertension, inflammation, renal disease progression, and cardiovascular disease. However, no data are available regarding the effect of allopurinol in patients with chronic kidney disease.Design, setting, participants, & measurements: We conducted a prospective, randomized trial of 113 patients with estimated GFR (eGFR)