Multimodal e-mental health treatment for depression: a feasibility trial.
Multimodal e-mental health treatment for depression: a feasibility trial.
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DOI：
10.2196/jmir.1370
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发表时间：
2010-12-19
影响因子：
7.4
通讯作者：
McCarthy M Jr
中科院分区：
文献类型：
--
作者：
Mohr DC;Duffecy J;Jin L;Ludman EJ;Lewis A;Begale M;McCarthy M Jr
对抑郁症的互联网干预措施的依从性较差。本研究描述了旨在提高抑郁症的依从性和结果的多模式电子心理健康干预的可行性试验。该干预需要频繁的简短登录以进行自我监控和反馈，以及由理论驱动的手动协议指导的电子邮件和简短的电话支持。这项可行性试验的目的是检验我们的互联网干预加上手动电话支持计划是否会提高依从率并改善抑郁症的结果。这是为期 7 周干预的单臂可行性试验。在 21 名入组患者中，有 2 名 (9.5%) 退出治疗。 7 周内患者登录次数为 23.2 ± 12.2 次。所有指标的抑郁程度均显着降低，包括患者健康问卷抑郁量表 (PHQ-8)（科恩 d = 1.96，P < .001）、汉密尔顿抑郁量表（d = 1.34，P < .001）和重性抑郁发作的诊断（P < .001）。流失率远低于互联网研究或面对面干预试验中的结果，而且抑郁症的结果也很显着。这些发现支持为抑郁症患者提供多模式电子心理健康治疗的可行性。尽管根据这些数据做出任何明确的结论还为时过早，但它们确实支持启动一项随机对照试验，检查互联网和电话治疗抑郁症的独立和联合效果。
Internet interventions for depression have shown less than optimal adherence. This study describes the feasibility trial of a multimodal e-mental health intervention designed to enhance adherence and outcomes for depression. The intervention required frequent brief log-ins for self-monitoring and feedback as well as email and brief telephone support guided by a theory-driven manualized protocol. The objective of this feasibility trial was to examine if our Internet intervention plus manualized telephone support program would result in increased adherence rates and improvement in depression outcomes. This was a single arm feasibility trial of a 7-week intervention. Of the 21 patients enrolled, 2 (9.5%) dropped out of treatment. Patients logged in 23.2 ± 12.2 times over the 7 weeks. Significant reductions in depression were found on all measures, including the Patient Health Questionnaire depression scale (PHQ-8) (Cohen’s d = 1.96, P < .001), the Hamilton Rating Scale for Depression (d = 1.34, P < .001), and diagnosis of major depressive episode (P < .001). The attrition rate was far lower than seen either in Internet studies or trials of face-to-face interventions, and depression outcomes were substantial. These findings support the feasibility of providing a multimodal e-mental health treatment to patients with depression. Although it is premature to make any firm conclusions based on these data, they do support the initiation of a randomized controlled trial examining the independent and joint effects of Internet and telephone administered treatments for depression.
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影响因子：
4
作者：
DESMOND, DW;TATEMICHI, TK;HANZAWA, L
通讯作者：
HANZAWA, L
影响因子：
5.9
作者：
Cuijpers, Pim;van Straten, Annemieke;van Oppen, Patricia
通讯作者：
van Oppen, Patricia
影响因子：
7.4
作者：
Clarke G;Eubanks D;Reid E;Kelleher C;O'Connor E;DeBar LL;Lynch F;Nunley S;Gullion C
通讯作者：
Gullion C
影响因子：
3
作者：
Mohr, David C.;Ho, Joyce;Reifler, Douglas
通讯作者：
Reifler, Douglas
影响因子：
5.3
作者：
Sheehan, DV;Lecrubier, Y;Dunbar, GC
通讯作者：
Dunbar, GC