Antiretroviral Treatment Sharing among Female sex Workers Living with HIV in eThekwini (Durban), South Africa: Drivers and Implications for Treatment Success.

Antiretroviral Treatment Sharing among Female sex Workers Living with HIV in eThekwini (Durban), South Africa: Drivers and Implications for Treatment Success.
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DOI:
10.1177/23259582221110820
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发表时间:
2022-01
影响因子:
--
通讯作者:
Schwartz, Sheree
Schwartz, Sheree
中科院分区:
其他
文献类型:
--
作者:
Rock, Amelia;Comins, Carly;Mulumba, Ntambue;Young, Katherine;Mcingana, Mfezi;Guddera, Vijayanand;Hausler, Harry;Phetlhu, Rene;Baral, Stefan;Schwartz, Sheree

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在南非,估计有62%的女性性工作者感染了艾滋病毒。定性研究表明,FSW与同龄人分享抗逆转录病毒疗法(ART),以克服治疗障碍。我们定量描述了ART共享,其相关性,以及它与病毒抑制(VS)之间的关系FSW艾滋病毒感染者在eThekwini,南非。在接受抗逆转录病毒治疗的女性工作者中(n = 890),30%的人曾分享(给予和/或接受)抗逆转录病毒治疗。在调整后的模型中,酒精使用、非法药物使用、抑郁严重程度和身体/性暴力水平较高的人更有可能分享抗逆转录病毒治疗。在过去30天内给予同伴的药丸数量与VS可能性之间存在正的剂量反应关系(aPR:1.05,95% CI:1.02,1.08; p < 0.01)。给药可以加强同伴关系,这可能有助于ART的坚持。ART分布通过同行网络持有承诺作为上下文适当的干预措施,提高ART坚持FSW在这种情况下。
In South Africa, 62% of female sex workers (FSW) are estimated to be living with HIV. Qualitative research indicates that FSW share antiretroviral therapy (ART) with peers to surmount treatment barriers. We quantitatively described ART sharing, its correlates, and its relationship with viral suppression (VS) among FSW living with HIV in eThekwini, South Africa. Among FSW on ART (n = 890), 30% ever shared (gave and/or received) ART. Sharing ART was more likely among those with higher levels of alcohol use, illicit drug use, depression severity, and physical/sexual violence in the adjusted model. There was a positive, dose-response relationship between number of pills given to peers in the last 30 days and VS likelihood (aPR: 1.05, 95% CI: 1.02, 1.08; p < 0.01). Giving pills may strengthen peer relationships, which may facilitate ART adherence. ART distribution through peer networks holds promise as a context-appropriate intervention for improving ART adherence among FSW in this setting.
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