Direct Patterning of protein- and cell-resistant polymeric monolayers and microstructures

Direct Patterning of protein- and cell-resistant polymeric monolayers and microstructures
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DOI:
10.1002/adma.200305433
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发表时间:
2003-12-03
期刊:
影响因子:
29.4
通讯作者:
Langer, R
Langer, R
中科院分区:
材料科学1区
文献类型:
--
作者:
Khademhosseini, A;Jon, S;Langer, R

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引入了一种简单的技术来对蛋白质和细胞进行图案化,并对特征形貌进行精确控制(参见图,白色条表示20 μm)。该技术使用一种成型工艺和一种新型的聚(乙二醇)共聚物的组合,通过对制造工艺的简单修改,形成从聚合物单层到微结构的形貌特征。
A simple techniqueis introduced to pattern proteins and cells with precise control over the feature topography (see Figure, white bar indicates 20 μm). The technique uses a combination of a molding process and a novel poly(ethylene glycol) copolymer to form topographical features ranging from polymeric monolayers to microstructures via simple modifications to the fabrication process.