W-cells in the cat retina: correlated morphological and physiological evidence for two distinct classes.
W-cells in the cat retina: correlated morphological and physiological evidence for two distinct classes.
复制标题
猫视网膜中的 W 细胞：两个不同类别的相关形态和生理证据。
DOI：
10.1152/jn.1987.57.1.218
复制
发表时间：
1987
影响因子：
2.5
通讯作者：
Stanford,LR
中科院分区：
文献类型：
--
作者：
Stanford,LR
本文用细胞内记录和辣根过氧化物酶离子导入法研究了猫视网膜W细胞的形态。记录实验在体内制备中进行，以使这些视网膜神经节细胞的反应与这些神经元的先前功能研究进行比较。16注射和回收的视网膜W-细胞的生理和形态学特征进行了比较，从14视网膜X-细胞注射在相同的制剂类似的数据。发现视网膜W细胞的索马体大小分为两个不同的组。相位W细胞的胞体，在每个偏心率，小于紧张W细胞的胞体，两个分布之间没有重叠。紧张性W-细胞的索马大小落入先前描述的视网膜神经节细胞索马大小的“中等大小”范围内，并且与生理学鉴定的β-或X-细胞的索马大小相似，尽管略大。生理上分类为紧张性W细胞的所有细胞的树突状动脉是相似的。这种类型的每一个例子都有4到5个初级树突，从索马分支一小段距离，形成一个圆形或十字形的树突乔木。这些细胞的树突状阵列很容易从紧凑的树突状乔木的生理鉴定的X细胞区分。的树突状乔木的相位W-细胞的异质性更大，范围从稀疏，广泛的树突状乔木非常紧凑的树突状乔木与许多细分支。没有显着的相关性，发现树突状乔木的程度和距离无论是紧张的W-细胞或相位的W-细胞的中央区域。紧张性和阶段性的W-细胞的轴突彼此不同，从X-细胞上的一些不同的形态和生理措施。相位W-细胞的轴突的视网膜内段具有三组中最小的直径;视网膜中的X-细胞的轴突相对较大，并且强直W-细胞的轴突具有介于相位W-细胞和X-细胞之间的直径。虽然相当大的重叠之间的X-细胞，紧张性W-细胞，和相位W-细胞在其逆行lavenance视交叉的电刺激，视网膜内和视网膜外组件的传导速度的三组有显着不同。（400字处截断摘要）
Intracellular recording and iontophoresis of horseradish peroxidase were used to study the morphology of physiologically characterized W-cells in the cat retina. The recording experiments were performed in an in vivo preparation to allow the responses of these retinal ganglion cells to be compared with previous functional studies of these neurons. The physiological and morphological characteristics of 16 injected and recovered retinal W-cells were compared with similar data from 14 retinal X-cells injected in the same preparations. The soma sizes of retinal W-cells were found to fall into two distinct groups. The somata of the phasic W-cells, at every eccentricity, were smaller than the somata of tonic W-cells, with no overlap between the two distributions. Soma sizes of the tonic W-cells fell into the previously described “medium-sized” range of retinal ganglion cell soma sizes and were similar to, although slightly larger than, the soma sizes of physiologically identified beta- or X-cells. The dendritic arbors of all of the cells physiologically classified as tonic W-cells were similar. Every example of this type had four to five primary dendrites that branched a short distance from the soma to form a circular or cruciate dendritic arbor. The dendritic arrays of these cells were easily distinguishable from the compact dendritic arbors of the physiologically identified X-cells. The dendritic arbors of the phasic W-cells were much more heterogeneous, ranging from sparse, wide dendritic arbors to very compact dendritic arbors with many fine branches. No significant correlation was found between the extent of the dendritic arbor and the distance from the area centralis for either the tonic W-cells or the phasic W-cells. The axons of the tonic and phasic W-cells differed from one another and from X-cells on a number of different morphological and physiological measures. The intraretinal segments of the axons of the phasic W-cells had the smallest diameters of the three groups; the axons of X-cells in the retina were relatively large, and the axons of the tonic W-cells had diameters intermediate between the phasic W-cells and the X-cells. Although considerable overlap was seen between the X-cells, tonic W-cells, and phasic W-cells in their antidromic latencies to electrical stimulation of the optic chiasm, the intraretinal and extraretinal components of the conduction velocities of the three groups were significantly different.(ABSTRACT TRUNCATED AT 400 WORDS)