Development and accuracy evaluation of a degree of occlusion visualization system for roller pumps used in cardiopulmonary bypass
Development and accuracy evaluation of a degree of occlusion visualization system for roller pumps used in cardiopulmonary bypass
复制标题
体外循环滚子泵闭塞程度可视化系统的开发及精度评估
DOI：
10.1007/s10047-020-01211-x
复制
发表时间：
2021
期刊：
影响因子：
1.3
通讯作者：
Yambe T
中科院分区：
文献类型：
--
作者：
Fukaya A;Shiraishi Y;Inoue Y;Yamada A;Sahara G;Kudo T;Aizawa Y;Yambe T
在用于心肺转流（CPB）的滚子泵中，由于滚子对管的压缩而导致的管内堵塞程度或闭塞程度与溶血密切相关，紧密闭塞和非闭塞程度均促进溶血。目前还没有关于调节封闭性的方法的国际标准，并且施加在血液上的机械应力的量仍然未知。为了防止在使用滚子泵的CPB期间发生溶血，需要澄清和定量评估滚子泵的闭塞性的机械应力。在这项研究中，我们已经开发了一个程度的闭塞量化系统，构建了一个闭塞的管道内的红色光密度图像的流道形状，我们已经验证了这个系统的有效性。利用线性致动器，丙烯酸辊和滚道，用模拟血液粉末着色的溶液，和3/8英寸的氯乙烯管，该系统使用相机捕获闭塞管内的红色光密度图像，并使用公式操作系统构建管流动通道形状。为了验证该系统的准确性，我们将用闭塞程度量化系统构建的流动通道的横截面的厚度与在相同闭塞条件下固化的硅酮的横截面的厚度进行了比较。实验结果表明，该系统可以在管间隙较小的区域构建高精度的三维形状，并获得评价遮挡程度的定量指标。
In roller pumps used for cardiopulmonary bypass (CPB), the degree of blockage within the tube resulting from compression of the tube by the rollers, or the degree of occlusion, is closely related to hemolysis, with both tight occlusive and non-occlusive degrees promoting hemolysis. There are as yet no international standards regarding methods of adjusting occlusiveness, and the amount of mechanical stress exerted upon blood remains unknown. To prevent hemolysis during CPB using roller pumps, there is a need to clarify and quantitatively assess the mechanical stress of the occlusiveness of the roller pump. In this study, we have developed a degree of occlusion quantification system which constructs the flow channel shape within an occluded tube from red optical density images, and we have verified the validity of this system. Utilizing a linear actuator, an acrylic roller and raceway, a solution colored with simulated blood powder, and a 3/8-inch vinyl chloride tube, this system uses a camera to capture red optical density images within an occluded tube and constructs the tube flow channel shape using a formula manipulation system. To verify the accuracy of this system, we compared the thickness of a cross-section of the flow channel constructed with the degree of occlusion quantification system with the thickness of a cross-section of silicone cured under the same occlusion conditions. Our experiments indicated that for areas with a small tube gap, this system can construct highly accurate three-dimensional shapes and obtain quantitative indicators assessing the degree of occlusion.
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