Olfactory Dysfunction and Chronic Rhinosinusitis
Olfactory Dysfunction and Chronic Rhinosinusitis
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DOI：
10.1016/j.iac.2019.12.013
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发表时间：
2020-05-01
影响因子：
2.6
通讯作者：
Rowan, Nicholas R.
中科院分区：
文献类型：
--
作者：
Ahmed, Omar G.;Rowan, Nicholas R.
嗅觉功能障碍（OD）是慢性鼻窦炎（CRS）的主要症状之一，其患病率在CRS患者中为60%至80%。与无鼻息肉病的 CRS 患者相比，伴有鼻息肉病的 CRS 患者更常见。嗅觉功能下降与患者报告的生活质量（QOL）显着下降有关，尤其是抑郁症和对食物的享受。客观测量可以帮助详细了解 OD 程度，而主观测量可以帮助确定对患者的影响。药物治疗和手术治疗对 OD 的治疗反应各不相同。
Olfactory dysfunction (OD) is one of the cardinal symptoms of chronic rhinosinusitis (CRS), and its prevalence ranges from 60% to 80% in patients with CRS. It is much more common in CRS with nasal polyposis patients compared to CRS without nasal polyposis. Decreased olfactory function is associated with significant decreases in patient-reported quality of life (QOL), and notably, depression and the enjoyment of food. Objective measures can help detail the degree of OD, whereas subjective measures can help to determine in the impact on patient. There is variable treatment response to OD with both medical and surgical therapies.