Are people with an orofacial cleft at a higher risk of dental caries? A systematic review and meta-analysis
Are people with an orofacial cleft at a higher risk of dental caries? A systematic review and meta-analysis
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DOI：
10.1038/sj.bdj.2017.581
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发表时间：
2017-07-01
影响因子：
2.6
通讯作者：
Ness, A.
中科院分区：
文献类型：
--
作者：
Worth, V.;Perry, R.;Ness, A.
目的探讨先天性唇腭裂儿童患龋的危险性是否高于无唇腭裂儿童。方法以“唇腭裂”和“口腔卫生龋齿”为关键词进行检索。检索了从成立到2016年4月的10个数据库，以识别所有相关研究。所有数据均由两名独立审查员提取。主要结果指标是龋坏，缺失，填充表面/牙齿指数（dmfs/dmft或DMFS/DMFT）。结果24篇文献符合入选标准。所有的研究都是观察性的。22项研究适合纳入荟萃分析。dmft的总体汇总平均差异为0.63（95% CI：0.47 - 0.79），DMFT为0.28（95% CI：0.22 - 0.34）。结论唇腭裂患者乳牙列和恒牙列患龋率均较高。
Objective To establish whether children born with an orofacial cleft have a higher risk of dental caries than individuals without cleft. Design A systematic review and meta-analysis Methods The search strategy was based on the key words 'cleft lip palate' and 'oral hygiene caries decay'. Ten databases were searched from their inception to April 2016 to identify all relevant studies. All data were extracted by two independent reviewers. The primary outcome measure was caries measured by the decayed, missing, filled surfaces/teeth index (dmfs/dmft or DMFS/DMFT). Results Twenty-four studies met the selection criteria. All of the studies were observational. Twenty-two studies were suitable for inclusion in the meta-analysis. The overall pooled mean difference in dmft was 0.63 (95% CI: 0.47 to 0.79) and in DMFT was 0.28 (95% CI: 0.22 to 0.34). Conclusion Individuals with cleft lip and/or palate have higher caries prevalence, both in the deciduous and the permanent dentitions.