Maternal serum copper and zinc concentrations in normal and small-for-date pregnancies.
Maternal serum copper and zinc concentrations in normal and small-for-date pregnancies.
复制标题
正常妊娠和小月妊娠的母体血清铜和锌浓度。
DOI：
10.1159/000299083
复制
发表时间：
1984
影响因子：
2.1
通讯作者：
R. Erkkola
中科院分区：
文献类型：
--
作者：
P. Kiilholma;M. Grönroos;P. Liukko;P. Pakarinen;H. Hyörä;R. Erkkola
对20例非妊娠健康月经妇女和20例妊娠妇女在孕1、2、3周和产后5周的血清铜、锌水平进行了纵向研究。此外，还对106名女性的横截面人口进行了研究。此外，对13名孕期较小(SFD)婴儿的孕妇进行了铜和锌浓度的测量；这是在怀孕的第三个月进行的。非孕妇女血清铜含量为0.91+/-0.19 mg/L，孕期显著高于未孕妇女(孕1、中、晚期分别为1.48+/-0.31、1.91+/-0.25、2.20+/-0.36 mg/L)，产后5周仍高于非孕妇女(1.09+/-0.17 mg/L)。在横断面人群中，血清铜和锌的值与纵向研究中的值相同。将妊娠晚期血清铜的纵向和横断值相结合，平均水平(2.23+/-0.40 mg/L)显著高于三七总病组(2.06+/-0.25 mg/L)。补锌组血清锌(0.48+/-0.12 mg/L)与正常妊娠值无显著差异。
Serum concentrations of copper (Cu) and zinc (Zn) were determined in 20 non-pregnant healthy menstruating women and in 20 pregnant women during the 1st, 2nd and 3rd trimesters and 5 weeks postpartum as a longitudinal study. Also a cross-sectional population of 106 women was studied. Further, Cu and Zn concentrations were measured in 13 pregnant women who gave birth to small-for-date (SFD) infants; this was done during the 3rd trimester of pregnancy. The serum Cu concentration in nonpregnant women was 0.91 +/- 0.19 mg/l. During pregnancy it was significantly higher (1.48 +/- 0.31, 1.91 +/- 0.25 and 2.20 +/- 0.36 mg/l during the 1st, 2nd and 3rd trimesters, respectively) and 5 weeks postpartum it was still higher (1.09 +/- 0.17 mg/l) than in the nonpregnant women. In the cross-sectional population, serum Cu and Zn values were of the same magnitude as in the longitudinal study. When longitudinal and cross-sectional values of serum Cu during the 3rd trimester were combined, the mean level (2.23 +/- 0.40 mg/l) was significantly higher than that in the SFD group (2.06 +/- 0.25 mg/l). Serum Zn in the SFD group (0.48 +/- 0.12 mg/l) did not differ significantly from the normal pregnant values.