Refractory gastric ulcer with abundant IgG4-positive plasma cell infiltration: A case report

Refractory gastric ulcer with abundant IgG4-positive plasma cell infiltration: A case report
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DOI:
10.3748/wjg.v16.i17.2183
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发表时间:
2010-05-07
影响因子:
4.3
通讯作者:
Goto, Hidemi
Goto, Hidemi
中科院分区:
医学2区
文献类型:
--
作者:
Fujita, Takayoshi;Ando, Takafumi;Goto, Hidemi

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我们描述了一名 77 岁男性,患有难治性胃溃疡,在根除幽门螺杆菌治疗后病情恶化。病理学显示胃病灶处有明显的IgG4阳性浆细胞浸润,这使我们怀疑IgG4相关的硬化性疾病。据我们所知,这是首例不以自身免疫性胰腺炎为主要表现的IgG4相关性胃溃疡的报道。 (C)2010年百事登。版权所有。
We describe a 77-year-old man with refractory gastric ulcer that worsened after Helicobacter pylori eradication therapy. Pathology showed marked infiltration of IgG4-positive plasma cells in the gastric lesions, which led us to suspect IgG4-related sclerosing disease. To the best of our knowledge, this is the first report of IgG4-related gastric ulcer without the main manifestation of autoimmune pancreatitis. (C) 2010 Baishideng. All rights reserved.