Parent-child hostility and child ADHD symptoms: a genetically sensitive and longitudinal analysis
Parent-child hostility and child ADHD symptoms: a genetically sensitive and longitudinal analysis
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DOI：
10.1111/j.1469-7610.2009.02107.x
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发表时间：
2009-12-01
影响因子：
7.6
通讯作者：
Thapar, Anita
中科院分区：
文献类型：
--
作者：
Lifford, Kate J.;Harold, Gordon T.;Thapar, Anita
背景：注意力缺陷多动障碍（ADHD）儿童的家庭报告家庭内冲突的发生率较高，亲子关系更为消极。本研究采用两个互补设计检验父母与子女的消极关系是否对ADHD症状有危险作用。方法：第一个样本包括886对11-17岁的双胞胎，来自一项基于人群的双胞胎研究。第二个样本来自一项纵向社区研究，包括282名父母及其11-14岁的子女。问卷被用来评估ADHD症状和母子和父子关系中的敌意。双变量遗传分析被用来测试的贡献，遗传和环境因素之间的关联亲子敌意和ADHD症状的双胞胎样本。交叉滞后和互惠效应模型被用来测试亲子敌意和ADHD症状之间的双向关系，随着时间的推移在纵向study.Results：对于男孩，遗传和环境因素都有助于母子敌意和ADHD症状之间的联系，但遗传因素单独解释了父子敌意和ADHD症状之间的关联。对于女孩来说，ADHD症状与母女敌意以及父子敌意之间的关联仅归因于遗传因素。这项纵向研究提供了男孩多动症症状在一段时间内和不同时间内影响母子敌意的证据。有没有影响在相反的direction.Conclusions：一个因果关系的假设，影响ADHD症状的家庭关系不支持。男孩的ADHD症状似乎对母子敌意有环境介导的影响。
Background:Families of children with attention-deficit/hyperactivity disorder (ADHD) report higher rates of conflict within the family and more negative parent-child relationships. This study aimed to test whether negative parent-child relationships have a risk effect on ADHD symptoms using two complementary designs.Method:The first sample included 886 twin pairs, aged 11-17 years, derived from a population-based twin study. The second sample was derived from a longitudinal community study and included 282 parents and their children, aged 11-14 years. Questionnaires were used to assess ADHD symptoms and hostility in the mother-child and father-child relationship. Bivariate genetic analysis was used to test the contribution of genetic and environmental factors to the association between parent-child hostility and ADHD symptoms in the twin sample. Cross-lagged and reciprocal effects models were used to test for a bidirectional relationship between parent-child hostility and ADHD symptoms over time in the longitudinal study.Results:For boys, both genetic and environmental factors contributed to the link between mother-son hostility and ADHD symptoms, but genetic factors alone explained the association between father-son hostility and ADHD symptoms. For girls, the association between ADHD symptoms and mother-daughter hostility as well as father-child hostility was attributed to genetic factors alone. The longitudinal study provided evidence of boys' ADHD symptoms impacting upon mother-son hostility both within and across time. There were no effects in the opposite direction.Conclusions:A causal hypothesis of family relations influencing ADHD symptoms was not supported. Boys' ADHD symptoms appear to have an environmentally mediated impact upon mother-son hostility.