Evaluation of age-related changes in lumbar facet joints using T2 mapping
Evaluation of age-related changes in lumbar facet joints using T2 mapping
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DOI：
10.1016/j.jos.2019.02.017
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发表时间：
2020-01-01
影响因子：
1.7
通讯作者：
Nagashima, Hideki
中科院分区：
文献类型：
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作者：
Enokida, Shinpei;Tanishima, Shinji;Nagashima, Hideki
背景：本研究的目的是研究无腰椎疾患、年龄在20 ~ 70岁的受试者腰椎突关节（FJ）的T2值，并评价年龄与T2值的相关性。同时，我们采用与FJ相同的方法研究了腰椎椎间盘（IVD）的T2值，并评价了FJ与IVD的T2值的相关性。方法：我们调查了60名志愿者（男30名，女30名），他们来自6个年龄组，20 - 70岁（每10年10名，男5名，女5名）。我们在轴位像测量FJ在L4/5水平的T2值，在中线矢状像测量IVD（髓核、NP、纤维前后环、AAF和PAF）在L4/5水平的T2值。探讨年龄与FJ T2值的相关性，以及FJ T2值与IVD的相关性。结果：年龄与FJ T2值呈正相关（r = 0.717）。年龄与IVD T2值呈负相关（NP; r = -0.728， AAF; r = -0.696， PAF; r = -0.580）。FJ与IVD T2值呈负相关（NP; r = -0.575， AAF; r = -0.617， PAF; r = -0.492）。结论：FJ的T2值随着年龄的增长而明显增高。我们的研究结果表明，即使在没有腰椎疾病的受试者中，T2定位也可以检测与衰老相关的FJ退行性改变。本研究的结果将作为FJ T2值的参考数据，以便利用T2映射来评价腰痛与FJ的关系。(C) 2019日本骨科协会。Elsevier B.V.版权所有。
Background: The purpose in this study is to investigate the T2 value of lumbar facet joint (FJ) in subjects without lumbar spinal disorders, age from 20s to 70s, using T2 mapping, and to evaluate the correlation between age and T2 value. And also, we investigated the T2 value of lumbar intervertebral disc (IVD) in the same way as FJ, and evaluated the correlation between the T2 value of FJ and that of IVD.Methods: We investigated 60 volunteers (30 male, 30 female), who were recruited from six age groups, 20s70s (10 subjects in each decade; 5 male, 5 female). We measured the T2 values of FJ at the L4/5 level in axial image and those of IVD (nucleus pulposus; NP, anterior and posterior annulus fibrosus; AAF and PAF) at the L4/5 level in midline sagittal image. We investigated the correlation between age and T2 value of FJ, and the correlation between the T2 value of FJ and that of IVD.Results: There was a strong positive correlation between age and T2 value of FJ (r = 0.717). Age and T2 values of IVD were negatively correlated (NP; r = -0.728, AAF; r = -0.696, PAF; r = -0.580). There was a negative correlation between T2 value of FJ and that of IVD (NP; r = -0.575, AAF; r = -0.617, PAF; r = -0.492).Conclusions: T2 value of FJ was significantly increased as age rose. Our results suggest that T2 mapping could detect the degenerative changes of FJ related to aging even in subjects without lumbar spinal disorders. The results of this study will be the reference data of FJ T2 value in order to evaluate the relationship between low back pain and FJ using T2 mapping. (C) 2019 The Japanese Orthopaedic Association. Published by Elsevier B.V. All rights reserved.