Short bowel syndrome: a review of management options.
Short bowel syndrome: a review of management options.
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DOI：
10.4103/1319-3767.82573
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发表时间：
2011-07
期刊：
影响因子：
--
通讯作者：
Rodrigues G
中科院分区：
文献类型：
--
作者：
Seetharam P;Rodrigues G
广泛的肠道切除经常导致消化和/或营养吸收不足，这种情况称为短肠综合征（SBS）。这种具有挑战性的情况需要专门的多学科团队努力克服这些患者的发病率和死亡率。随着重症监护管理的进步，越来越多的患者在大面积肠切除术后立即发病，并出现SBS。几种治疗方法，包括肠外营养（PN），肠道康复和外科手术，以重建肠道已被用于这些患者。新的饮食方法、药物治疗和及时的手术干预都有助于改善这些患者的预后。然而，这些治疗仅部分纠正了肠功能降低的潜在问题，并且成功率有限，导致30%至50%的死亡率。然而，越来越多的经验和令人鼓舞的结果肠移植增加了一个新的层面的SBS的管理。关于SBS的现有文献是详尽的，但不确定。我们对科学文献和电子媒体进行了综述，检索词为“短肠综合征，SBS和SBS的进展”，并试图全面介绍这一主题，重点是其管理的最新进展。
Extensive resection of the intestinal tract frequently results in inadequate digestion and/or absorption of nutrients, a condition known as short bowel syndrome (SBS). This challenging condition demands a dedicated multidisciplinary team effort to overcome the morbidity and mortality in these patients. With advances in critical care management, more and more patients survive the immediate morbidity of massive intestinal resection to present with SBS. Several therapies, including parenteral nutrition (PN), bowel rehabilitation and surgical procedures to reconstruct bowel have been used in these patients. Novel dietary approaches, pharmacotherapy and timely surgical interventions have all added to the improved outcome in these patients. However, these treatments only partially correct the underlying problem of reduced bowel function and have limited success resulting in 30% to 50% mortality rates. However, increasing experience and encouraging results of intestinal transplantation has added a new dimension to the management of SBS. Literature available on SBS is exhaustive but inconclusive. We conducted a review of scientific literature and electronic media with search terms 'short bowel syndrome, advances in SBS and SBS’ and attempted to give a comprehensive account on this topic with emphasis on the recent advances in its management.
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影响因子：
24.5
作者：
NIGHTINGALE, JMD;KAMM, MA;LENNARDJONES, JE
通讯作者：
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影响因子：
17.3
作者：
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影响因子：
24.5
作者：
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通讯作者：
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影响因子：
3.1
作者：
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通讯作者：
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影响因子：
24.5
作者：
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通讯作者：
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