Delayed Allergic Reaction to Secondary Administrated Epidural Hyaluronidase
Delayed Allergic Reaction to Secondary Administrated Epidural Hyaluronidase
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DOI：
10.3344/kjp.2015.28.2.153
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发表时间：
2015-04
期刊：
影响因子：
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通讯作者：
Administrated Epidural Hyaluronidase;A. Park;W. Kim;B. Heo
中科院分区：
文献类型：
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作者：
Administrated Epidural Hyaluronidase;A. Park;W. Kim;B. Heo
我们报告一个罕见的病例延迟超敏反应引起的透明质酸酶过敏后腰椎经椎间孔硬膜外阻滞。使用皮内皮肤试验，我们提供的证据表明，全身性过敏反应是由透明质酸酶过敏引起的。据我们所知，这是一个罕见的硬膜外透明质酸酶延迟超敏反应的病例，包括最初接触透明质酸酶，在先前的阻滞中没有随后的过敏反应，随后在第二次硬膜外阻滞中对透明质酸酶的延迟反应。
We are reporting a rare case of a delayed hypersensitivity reaction caused by hyaluronidase allergy following a lumbar transforaminal epidural block. Using an intradermal skin test, we have provided evidence that the systemic allergic reaction resulted from hypersensitivity to hyaluronidase. To our knowledge, this is a rare case of a delayed hypersensitivity reaction to epidural hyaluronidase, comprised of an initial exposure to hyaluronidase with no subsequent allergic response in prior block followed by a subsequent delayed reaction to hyaluronidase during a second epidural block.