Preliminary report: A serious link between adiponectin levels and metabolic syndrome in a Korean nondiabetic population
Preliminary report: A serious link between adiponectin levels and metabolic syndrome in a Korean nondiabetic population
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DOI：
10.1016/j.metabol.2009.07.031
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发表时间：
2010-03-01
影响因子：
9.8
通讯作者：
You, Joshua (Sung) H.
中科院分区：
文献类型：
--
作者：
Koh, Sang-Back;Park, Jong-Ku;You, Joshua (Sung) H.
这项大规模的横断面调查强调了在非糖尿病韩国人群（N = 6634）中脂联素水平与一些代谢综合征组分之间的关系。在多变量逻辑回归模型中，在对年龄、胰岛素抵抗的稳态模型评估、体重指数、吸烟史、C - 反应蛋白和低密度脂蛋白胆固醇进行调整后，脂联素水平在男性和女性中均与代谢综合征呈负相关（P <.05）。脂联素水平被发现是代谢综合征的一个重要影响因素。我们的研究结果表明，即使在代谢综合征高风险的非糖尿病人群中，脂联素也是一种重要的生物标志物。（C）2010爱思唯尔公司。保留所有权利。
This large-scale cross-sectional investigation highlights the relationships between adiponectin levels and a number of metabolic syndrome components in a nondiabetic Korean population (N = 6634). In a multivariate logistic regression model, after adjustment for age, homeostasis model assessment of insulin resistance, body mass index, smoking history, C-reactive protein, and low-density lipoprotein cholesterol, adiponectin levels were inversely related with metabolic syndrome in men and women (P < .05). Adiponectin level was found to be a significant contributor to metabolic syndrome. Our findings suggest that adiponectin is an important biomarker even in a nondiabetic population at high risk of metabolic syndrome. (C) 2010 Elsevier Inc. All rights reserved.