Children and adults with primary antibody deficiencies gain quality of life by subcutaneous IgG self-infusions at home

Children and adults with primary antibody deficiencies gain quality of life by subcutaneous IgG self-infusions at home
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DOI:
10.1016/j.jaci.2004.06.053
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发表时间:
2004-10-01
影响因子:
14.2
通讯作者:
Borte, M
Borte, M
中科院分区:
医学1区
文献类型:
--
作者:
Gardulf, A;Nicolay, U;Borte, M

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背景:大量儿童和成人的一抗缺乏需要终身IgG替代治疗。目前尚不清楚替代治疗的选择对患者的健康相关生活质量(HRQOL)和治疗满意度(TS)有何影响。目的:探讨从医院静脉注射IgG(IVIG)转为家庭皮下注射IgG(SCIG)治疗是否会改善HRQOL和TS。方法:15例儿童(
Background: A large number of children and adults with primary antibody deficiencies need lifelong IgG replacement therapy. It is mostly unknown what effect the choice of replacement therapy has on the patients' health-related quality of life (HRQOL) and treatment satisfaction (TS).Objective: To investigate whether a switch from hospital-based intravenous IgG (IVIG) to home-based subcutaneous IgG (SCIG) therapy would improve the HRQOL and TS.Methods: Fifteen children (