Cognitive functioning and instrumental activities of daily living in late-life bipolar disorder
Cognitive functioning and instrumental activities of daily living in late-life bipolar disorder
复制标题
DOI：
10.1097/jgp.0b013e31802dd367
复制
发表时间：
2007-02-01
影响因子：
7.2
通讯作者：
Mulsant, Benoit H.
中科院分区：
文献类型：
--
作者：
Gildengers, Ariel G.;Butters, Meryl A.;Mulsant, Benoit H.
目的：探讨老年双相情感障碍患者认知功能与工具性日常生活活动(IADL)的关系。方法：对20例年龄61~86岁的双相情感障碍患者进行综合神经心理测试。对其中19名患者进行了结构化的基于家庭表现的IADLS评估。结果：与年龄相同的参照者相比，双相受试者在信息处理速度和执行功能方面表现较差。IADL成绩与这些认知领域有很强的相关性。结论：在双相情感障碍的老年患者中，信息处理速度和执行功能的下降是认知功能的特征，并与较差的IADL表现有关。
Objective: The authors report on the relationship between cognitive functioning and instrumental activities of daily living (IADLs) in elderly, clinically euthymic adults with bipolar disorder. Methods: Twenty patients with bipolar disorder (age range: 61-86 years) were administered comprehensive neuropsychologic testing. Structured in-home performance-based assessments of IADLs were performed in 19 of these patients. Results: Relative to age-equated comparators, bipolar subjects performed worse in information-processing speed and executive functioning. IADL performance was strongly correlated with these cognitive domains. Conclusions: In euthymic elderly patients with bipolar disorder, decrements in information processing speed and executive functioning characterize cognitive function and are associated with poorer IADL performance.