RACE, NUTRITIONAL-STATUS, AND SURVIVAL FROM BREAST-CANCER
RACE, NUTRITIONAL-STATUS, AND SURVIVAL FROM BREAST-CANCER
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DOI：
10.1093/jnci/82.21.1684
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发表时间：
1990-11-07
影响因子：
10.3
通讯作者：
BROWN, RL
中科院分区：
文献类型：
--
作者：
COATES, RJ;CLARK, WS;BROWN, RL
在1975-1979年期间，对1960名美国乔治亚州诊断为乳腺癌的女性进行了研究，研究了营养状况对黑人和白人女性乳腺癌患者生存差异的影响。根据疾病分期、社会经济地位和其他预后因素对数据进行调整后，黑人妇女的生存率较低。在每个分期分类中，较低水平的血清白蛋白和血红蛋白以及较高的相对体重在黑人中更为常见，并且与较差的生存率独立相关。在患有第三阶段疾病的妇女中，对这些变量进行调整大大降低了黑人的超额死亡率，这表明种族间生存差异可能部分地由营养状况或疾病程度的差异来解释。
The effects of nutritional status on differences in the survival of black and white women with breast cancer were studied in a cohort of 1,960 Georgia [USA] women diagnosed duirng 1975-1979. After data were adjusted for stage of disease, socioeconomic status, and other prognostic factors, poorer survival rates were shown in black women. Within each stage classification, lower levels of serum albumin and hemoglobin and higher relative body weight were more common among blacks and were independently associated with poorer survival. Among women with stage 3 disease, adjustment for these variables substantially reduced the excess mortality rate among blacks, suggesting that racial differences in survival may be partly explained by differences in nutritional status or extent of disease with stage.