Physiological Traits and Adherence to Obstructive Sleep Apnea Treatment in Patients with Stroke.

Physiological Traits and Adherence to Obstructive Sleep Apnea Treatment in Patients with Stroke.
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中风患者的生理特征和阻塞性睡眠呼吸暂停治疗的依从性。

DOI:
10.1164/rccm.201911-2203le
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发表时间:
2020
影响因子:
24.7
通讯作者:
Yaggi,HenryK
Yaggi,HenryK
中科院分区:
医学1区
文献类型:
--
作者:
Zinchuk,AndreyV;Redeker,NancyS;Chu,Jen-Hwa;Liang,Jiasheng;Stepnowsky,Carl;Brandt,CynthiaA;Bravata,DawnM;Wellman,Andrew;Sands,ScottA;Yaggi,HenryK

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方法我们对急性卒中或短暂性脑缺血发作(TIA)患者OSA治疗的随机对照试验(NCT01446913)进行了二次数据分析。84例患者接受无人值守的多导睡眠监测,并根据呼吸暂停低通气指数≥5次/小时开出持续正压呼吸机,排除未开始持续正压正压的患者(n=4)、多导睡眠图信号不足以测量阻塞性睡眠呼吸暂停的患者(n=18)、或因急性疾病(如肺炎;n=2)而停止持续正压治疗的患者(n=2),选择分析样本60例。母体研究包括两个干预分支:“标准”和“增强”(“标准”与行为CPAP依从性咨询)。由于两组患者在依从性方面没有差异,因此在分析中将两组患者汇集在一起(5)。
MethodsWe performed a secondary data analysis of a randomized controlled trial (SleepTight; NCT01446913) of OSA management among patients with acute stroke or transient ischemic attack (TIA)(2). Of the 84 patients who underwent unattended polysomnography and were prescribed CPAP on the basis of the apnea–hypopnea index≥ 5 events/h, the analytic sample (n= 60) was selected by excluding those who did not start CPAP (n= 4), had inadequate polysomnography signals to measure OSA traits (n= 18), or terminated CPAP use because of acute illness (eg, pneumonia; n= 2)(2). The parent study included two intervention arms:“standard” and “enhanced”(“standard” with behavioral CPAP adherence counseling). Patients from both arms were pooled in the analyses because there were no differences in adherence between the two groups (5).
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