Aggregative Multicellularity Evolved Independently in the Eukaryotic Supergroup Rhizaria
Aggregative Multicellularity Evolved Independently in the Eukaryotic Supergroup Rhizaria
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DOI：
10.1016/j.cub.2012.04.021
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发表时间：
2012-06-19
期刊：
影响因子：
9.2
通讯作者：
Roger, Andrew J.
中科院分区：
文献类型：
--
作者：
Brown, Matthew W.;Kolisko, Martin;Roger, Andrew J.
多细胞生命形式已经进化了许多次，独立地产生了生物的多样性，如动物、植物和真菌，它们共同构成了可见的生物圈。然而，多细胞生命在真核生物中的分布远不止这三种谱系。多细胞生物的一种特别常见的形式是社会性聚集体结果的生活方式，即单个细胞结合形成“真菌样”的果皮。这一复杂的发育过程需要成千上万个细胞协同工作的相互作用，因“细胞黏菌”盘基钢霉（Dictyostelium disideum）而闻名，它成为一种重要的模式生物[1]。虽然在5个主要的真核生物类群中已经发现了嗜索原菌谱系[2-8]，但普遍存在且分布在全球的Guttulinopsis vulgaris却没有得到适当的分类。在这里，我们通过对159个蛋白质数据集的系统基因组分析证明，G. vulgaris是根状菌的成员，因此是已知能够聚集多细胞的真核生物超群的第一个成员。
Multicellular forms of life have evolved many times, independently giving rise to a diversity of organisms such as animals, plants, and fungi that together comprise the visible biosphere. Yet multicellular life is far more widespread among eukaryotes than just these three lineages. A particularly common form of multicellularity is a social aggregative fruiting lifestyle whereby individual cells associate to form a "fungus-like" sorocarp. This complex developmental process that requires the interaction of thousands of cells working in concert was made famous by the "cellular slime mold" Dictyostelium discoideum, which became an important model organism [1]. Although sorocarpic protistan lineages have been identified in five of the major eukaryote groups [2-8], the ubiquitous and globally distributed species Guttulinopsis vulgaris has eluded proper classification. Here we demonstrate, by phylogenomic analyses of a 159-protein data set, that G. vulgaris is a member of Rhizaria and is thus the first member of this eukaryote supergroup known to be capable of aggregative multicellularity.