Adolescent obesity, change in weight status, and hypertension: racial/ethnic variations.
Adolescent obesity, change in weight status, and hypertension: racial/ethnic variations.
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DOI：
10.1161/hypertensionaha.111.00214
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发表时间：
2013-02
期刊：
影响因子：
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通讯作者：
Gary-Webb TL
中科院分区：
文献类型：
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作者：
Suglia SF;Clark CJ;Gary-Webb TL
我们试图确定青春期和青年期之间体重状况的变化是否与青少年患高血压的风险有关，以及在国家青少年健康纵向研究中是否存在性别和种族/民族差异。样本仅限于自认为是非裔美国人、西班牙裔或白色非西班牙裔的参与者（N=8543）。在青春期（平均16岁）测量身高和体重，并在成年期（平均29岁）再次测量身高和体重。我们将参与者的体重分为四组：保持正常体重;体重增加（青春期体重正常，成年后肥胖）;体重减轻（青春期超重/肥胖，成年后非肥胖）;长期超重/肥胖。高血压定义为成年期测量的收缩压至少140 mmHg或舒张压至少90 mmHG，或使用抗高血压药物。注意到所有性别和种族/民族的成年肥胖者患高血压的风险更高。此外，那些长期超重/肥胖的人患高血压的风险更高，优势比范围从西班牙裔男性的2.7到西班牙裔女性的6.5。除了非洲裔美国男性，那些在随访期间体重减轻的人与那些保持正常体重的人相比，风险没有显着增加。总的来说，那些在成年期体重增加的人和那些从青春期到青年期仍然肥胖的人患高血压的风险增加。这些数据为预防策略提供了进一步的证据，这些策略可以在生命的早期开始，以减少或延迟年轻人慢性病的发作。
We sought to determine whether change in weight status between adolescence and young adulthood was associated with the risk of developing hypertension among adolescents and whether gender and racial/ethnic group differences existed in the National Longitudinal Study of Adolescent Health. The sample was restricted to participants who self-identified as African-American, Hispanic or White Non-Hispanic (N=8543). Height and weight were measured in adolescence (mean 16yrs), and again in adulthood (mean 29yrs). We categorized the participants weight into four groups: stayed normal weight; gained weight (normal weight in adolescence and obese in adulthood); lost weight (overweight/obese in adolescence non-obese in adulthood); chronically overweight/obese. Hypertension was defined as measured systolic blood pressure of at least 140mmHg or diastolic blood pressure of at least 90mmHG measured in adulthood, or use of antihypertensive medications. A higher risk of hypertension was noted for all gender and racial/ethnic groups who became obese in adulthood. Furthermore, those who were chronically overweight/obese were at higher risk of hypertension for all groups with odds ratios ranging from 2.7 in Hispanic men to 6.5 in Hispanic women. Except for African-American men, those who lost weight during follow up had no significant increased risk compared to those who maintained normal weight. Overall, there was an increased risk of hypertension for those who gained weight in adulthood and among those who remained obese from adolescence to young adulthood. These data give further evidence for prevention strategies that begin earlier in life to reduce or delay the onset of chronic disease in young adults.