Distribution and chromosomal characterization of the anopheles gambiae complex in Angola

Distribution and chromosomal characterization of the anopheles gambiae complex in Angola
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DOI:
10.4269/ajtmh.2008.78.169
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发表时间:
2008-01-01
影响因子:
3.3
通讯作者:
Petrarca, Vincenzo
Petrarca, Vincenzo
中科院分区:
医学4区
文献类型:
--
作者:
Calzetta, Maria;Santolamazza, Federica;Petrarca, Vincenzo

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2001 年至 2005 年,在安哥拉各地对冈比亚按蚊群 (N = 1,336) 的蚊子进行了采样,以鉴定类群、研究倒位多态性并检测恶性疟原虫的环子孢子蛋白。冈比亚按蚊 s.s.在所有网站中都找到了;在热带干旱和半荒漠带地区,其特征为M型,而在相对湿润和人类化程度较低的地区,S型则占主导地位。这两种形式的特征都是低度染色体多态性,仅基于 2La 倒位,这种模式通常与 An 相关。来自森林、潮湿和衍生稀树草原地区的冈比亚种群。出乎意料的是,在干燥/荒漠前地区收集的 M 型种群中也观察到了这种模式,在这些地区,这种类型比 An 型更占主导地位。 arabiensis,也在中部/内陆地点检测到。黑按蚊在北部沿海地区被发现。 534 An 中的三个。冈比亚船队恶性疟原虫CS蛋白呈阳性,而1.05 An. falciparum CS蛋白均呈阳性。梅拉斯呈阳性。
Mosquitoes of the Anopheles gambiae complex (N = 1,336) were sampled (2001-2005) across Angola to identify taxa, study inversion polymorphisms, and detect the circumsporozoite protein of Plasmodium falciparum. Anopheles gambiae s.s. was found in all sites; it was characterized as M-form in localities of the tropical dry and semi-desertic belts, whereas the S-form was predominant in comparatively more humid and less anthropized sites. Both forms were characterized by low degrees of chromosomal polymorphism based solely on the 2La inversion, a pattern usually associated with An. gambiae populations from forested, humid, and derived savanna areas. Unexpectedly, this pattern was also observed in M-form populations collected in dry/pre-desertic areas, where this form largely predominates over An. arabiensis, which was also detected in central/inland sites. Anopheles melas was found in northern coastal sites. Three of 534 An. gambiae s.s. were positive for P. falciparum CS-protein, whereas none of the 1.05 An. melas were positive.