Anti-HIV agents derived from the ent-kaurane diterpenoid linearol
Anti-HIV agents derived from the ent-kaurane diterpenoid linearol
复制标题
DOI：
10.1021/np020029b
复制
发表时间：
2002-11-01
影响因子：
5.1
通讯作者：
Lee, KH
中科院分区：
文献类型：
--
作者：
Bruno, M;Rosselli, S;Lee, KH
研究了线性醇(1)的26种半合成的正烷衍生物的抗hiv作用。5个化合物（4、7、11、25和26）在H9淋巴细胞中显示出显著的抗HIV复制活性，EC50值在范围内
Twenty-six semisynthetic ent-kaurane derivatives of linearol (1) have been investigated for their anti-HIV effects. Five compounds (4, 7, 11, 25, and 26) showed significant activity against HIV replication in H9 lymphocyte cells with EC50 values in the range