Biologically meaningful coverage indicators for eliminating malaria transmission
Biologically meaningful coverage indicators for eliminating malaria transmission
复制标题
DOI：
10.1098/rsbl.2012.0352
复制
发表时间：
2012-10-23
期刊：
影响因子：
3.3
通讯作者：
Killeen, Gerry F.
中科院分区：
文献类型：
--
作者：
Kiware, Samson S.;Chitnis, Nakul;Killeen, Gerry F.
蚊子通过在室外或以动物为食来逃避与长效杀虫网和室内残留喷雾剂的接触，是许多热带国家的主要疟疾传播媒介。它们还可以在这些一线病媒控制措施实现高覆盖率的情况下主导残余传播。在大多数情况下，需要采取补充策略，将杀虫剂的覆盖范围扩大到房屋和人类之外，以消除疟疾传播。世界上疟疾传播系统的压倒性多样性和控制它们的最佳策略可以简单地概念化并映射到二维场景空间中，该二维场景空间由媒介从人类获得的血粉比例和人类在室内接触血粉的比例定义。
Mosquitoes, which evade contact with long-lasting insecticidal nets and indoor residual sprays, by feeding outdoors or upon animals, are primary malaria vectors in many tropical countries. They can also dominate residual transmission where high coverage of these front-line vector control measures is achieved. Complementary strategies, which extend insecticide coverage beyond houses and humans, are required to eliminate malaria transmission in most settings. The overwhelming diversity of the world's malaria transmission systems and optimal strategies for controlling them can be simply conceptualized and mapped across two-dimensional scenario space defined by the proportion of blood meals that vectors obtain from humans and the proportion of human exposure to them which occurs indoors.