Perhalo Ketones. VI. Aromatic Amino Derivatives of the Perhaloacetones
Perhalo Ketones. VI. Aromatic Amino Derivatives of the Perhaloacetones
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Perhalo 酮。
DOI：
10.1021/jo01015a010
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发表时间：
1965
期刊：
影响因子：
--
通讯作者：
J. Sibilia
中科院分区：
文献类型：
--
作者：
E. Gilbert;E. S. Jones;J. Sibilia
本文报道了由二氯丙酮、五氟一氯丙酮和六氟丙酮与各种芳香胺缩合合成的22种新甲醇。对甲苯磺酸催化剂的加入缩短了反应时间和温度，提高了六氟丙酮的产率，使氟氯丙酮有可能分离出确定的产物，并诱导了与低碱度胺的反应。对其中8个化合物进行了核磁共振结构研究。
Twenty-two new carbinols were prepared by condensing tetrafluorodichloro-, pentafluoromonochloro-, and hexafluoroacetones with various aromatic amines. Addition of p-toluenesulfonic acid catalyst reduces the reaction time and temperature and improves product yield with hexafluoroacetone, makes possible the isolation of definite products with the fluorochloroacetones, and induces reaction with amines of low basicity. Nmr structural studies were made on eight of the compounds.