The Th1 versus Th2 cytokine profile in cerebrospinal fluid after severe traumatic brain injury in infants and children.

The Th1 versus Th2 cytokine profile in cerebrospinal fluid after severe traumatic brain injury in infants and children.
复制标题

DOI：
10.1097/00130478-200107000-00013
复制
发表时间：
2001-07-01
期刊：
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
影响因子：
--
通讯作者：
Kochanek, Patrick M.
Kochanek, Patrick M.
中科院分区：
其他
文献类型：
--
作者：
Amick, Jonathan E.;Yandora, Kristin A.;Kochanek, Patrick M.

文献摘要

被引文献

相似文献

目的：通过量化婴儿和儿童脑脊液中Th1细胞因子（白细胞介素[IL]-2和IL-12）和Th2细胞因子（IL-6和IL-12）的浓度，进一步表征严重创伤性脑损伤（TBI）后Th1（促炎）和Th2（抗炎）细胞因子谱。设计：回顾性研究。单位：大学儿童医院。患者：24例重症TBI患儿住院(入院格拉斯哥昏迷评分，
OBJECTIVE: To further characterize the Th1 (proinflammatory) vs. the Th2 (antiinflammatory) cytokine profile after severe traumatic brain injury (TBI) by quantifying the ventricular cerebrospinal fluid concentrations of Th1 cytokines (interleukin [IL]-2 and IL-12) and Th2 cytokines (IL-6 and IL-12) in infants and children. DESIGN: Retrospective study. SETTING: University children's hospital. PATIENTS: Twenty-four children hospitalized with severe TBI (admission Glasgow Coma Scale score,