Obituary. Robert Simpson.
Obituary. Robert Simpson.
复制标题
讣告。
DOI：
10.1093/nar/gkh647
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发表时间：
2004
影响因子：
14.9
通讯作者：
Felsenfeld,Gary
中科院分区：
文献类型：
--
作者：
Felsenfeld,Gary
alpha 2 repressor to explore the role of the repressor in nucleosome positioning, the response of positioning to transcriptional activation, and the role of histone tails in controlling these events. This led in turn to studies of the role of the regulatory proteins TUP1 and SSN6 in alpha2 repression, an interest that remained strong at the time of his death.The continuity of Bob's interests from his earliest to his most recent work was consistent with his character. He was inventive as well as deliberate, thoughtful and thorough. In a field as amorphous (at least at its beginnings) as the one in which he chose to work, he was someone whose results could be depended upon for absolute reliability. That attribute, coupled with his originality, explains why his experiments and conclusions are just as important today as they were when he first published them. Bob was a very calm, dependable and kind colleague. Like many who choose to stay at NIH for long periods, he enjoyed working in the laboratory, and his papers describe many of his own experiments. He moved from the NIH in 1995 to accept the Verne Willaman Chair in Biochemistry and Molecular Biology at Penn State, where he was instrumental in turning his department into a major center for research in gene expression and chromatin structure. As he had while he was in Bethesda, he continued to attract outstanding young investigators to his laboratory; the influence of his training can be seen in the quality of the work that they continue to produce as independent investigators. Although I and many others regretted his departure from NIH, it was a pleasure to see him succeed so well in his new job and his many talents put to such good use. He was a deeply respected and admired member of our community, and all of us will greatly miss him as a colleague and friend.
