The differential absorptive activity of epithelial cells of the rat epididymus before and after castration
The differential absorptive activity of epithelial cells of the rat epididymus before and after castration
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去势前后大鼠附睾上皮细胞吸收活性的差异
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
J. Bedford
中科院分区：
文献类型：
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作者：
H. D. Moore;J. Bedford
辣根过氧化物酶被引入到大鼠附睾的管腔中，由上皮的柱状细胞在5分钟内被吸收，并且在更长的时间后被吸收。顶细胞，特别是在附睾头和尾部的透明细胞，分别表现出显着更大的内吞活性比主细胞在这两个位置。然而，在去势后14天内，由于雄激素缺乏的主细胞的内吞作用增加，各种细胞类型之间吸收活性的差异基本上被掩盖了。结果进行了简要的讨论，在不同的上皮细胞类型和分泌/吸收活性的附睾的功能。
Horseradish peroxidase introduced into the lumen of the rat epididymis was taken up by the columnar cells of the epithelium by five minutes and more so after longer periods. The apical cells and particularly the clear cells in the caput and cauda epididymidis, respectively, showed significantly greater endocytotic activity than the principal cell in both locations. Within 14 days after castration, however, such differences in absorptive activity among the various cell types were essentially obscured because of increased endocytosis by the androgen‐deficient principal cells. The results are discussed briefly in terms of the function of different epithelial cell types and secretory/absorptive activity in the epididymis.