The effect of cigarette smoking on hemoglobin levels and anemia screening.
The effect of cigarette smoking on hemoglobin levels and anemia screening.
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DOI：
10.1001/jama.1990.03450120068031
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发表时间：
1990-09
期刊：
影响因子：
--
通讯作者：
D. Nordenberg;R. Yip;N. Binkin
中科院分区：
文献类型：
--
作者：
D. Nordenberg;R. Yip;N. Binkin
使用第二次全国健康营养调查的数据，研究了吸烟与血红蛋白浓度和碳氧血红蛋白浓度之间的关系。在女性中，吸烟者的平均 (+/- SE) 血红蛋白水平为 137 +/- 0.4 g/L，显着高于从不吸烟者的平均血红蛋白水平 133 +/- 0.5 g/L。在男性中，吸烟者和从不吸烟者的平均血红蛋白水平分别为 156 +/- 0.4 和 152 +/- 0.5 g/L。戒烟者和从不吸烟者之间的平均血红蛋白没有显着差异。平均血红蛋白水平和碳氧血红蛋白水平随着每天吸烟数量的增加而逐渐增加。吸烟似乎会导致血红蛋白分布曲线普遍上移，从而降低了血红蛋白水平检测贫血的效用。在社会经济地位相当的女性中，吸烟者的贫血患病率为 4.8% +/- 0.6%，而从不吸烟者的贫血患病率为 8.5% +/- 1.2%。这项研究表明，应针对吸烟者调整最低血红蛋白截止值，以补偿吸烟对贫血检测的掩盖效应。
The relationships among cigarette smoking, hemoglobin concentration, and carboxyhemoglobin concentration were examined using data from the Second National Health and Nutrition Examination Survey. Among women, smokers had a mean (+/- SE) hemoglobin level of 137 +/- 0.4 g/L, significantly higher than the mean hemoglobin level of 133 +/- 0.5 g/L for never-smokers. Among men, the mean hemoglobin levels for smokers and never-smokers were 156 +/- 0.4 and 152 +/- 0.5 g/L, respectively. No significant difference in mean hemoglobin was noted between ex-smokers and never-smokers. Mean hemoglobin levels and carboxyhemoglobin levels increased progressively with the number of cigarettes consumed per day. Cigarette smoking seems to cause a generalized upward shift of the hemoglobin distribution curve, which reduces the utility of hemoglobin level to detect anemia. Among women of comparable socioeconomic status, the prevalence of anemia was 4.8% +/- 0.6% among smokers, compared with 8.5% +/- 1.2% among never-smokers. This study suggests that minimum hemoglobin cutoff values should be adjusted for smokers to compensate for the masking effect of smoking on the detection of anemia.