CYTOKINE EXPRESSION PROFILES ASSOCIATED WITH DISTINCT CLINICAL COURSES IN HEPATITIS A VIRUS-INFECTED CHILDREN

CYTOKINE EXPRESSION PROFILES ASSOCIATED WITH DISTINCT CLINICAL COURSES IN HEPATITIS A VIRUS-INFECTED CHILDREN
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DOI:
10.1097/inf.0b013e318258e808
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发表时间:
2012-08-01
影响因子:
3.6
通讯作者:
Panduro, Arturo
Panduro, Arturo
中科院分区:
医学4区
文献类型:
--
作者:
Fierro, Nora A.;Escobedo-Melendez, Griselda;Panduro, Arturo

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We determined the serum cytokine profiles during distinct hepatitis A virus-induced clinical courses in children. A significant overexpression of interleukin-1, interleukin-6, tumor necrosis factor-alpha and monocyte chemotactic protein-2 was found in children with intermediate liver injury, whereas the patients with minor liver injury had a significant increase of interleukin-8 and transforming growth factor-beta values.