Oxygen therapy strategies and techniques to treat hypoxia in COVID-19 patients.
Oxygen therapy strategies and techniques to treat hypoxia in COVID-19 patients.
复制标题
氧疗法策略和技术治疗COVID-19患者缺氧的技术。
DOI：
10.26355/eurrev_202010_23248
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发表时间：
2020-10
影响因子：
3.3
通讯作者：
中科院分区：
文献类型：
--
作者：
目的：缺氧是导致COVID-19患者多器官损伤和死亡的主要原因之一。积极的氧疗对缺氧的治疗是重要的，在挽救这些病人。我们总结了各种氧疗技术的机制、疗效和副作用，以及它们在COVID-19患者中治疗缺氧的现状或潜力。讨论了每种氧疗技术的获益风险比以及在COVID-19患者中使用它们的策略。高流量鼻导管氧疗（HFNO）是早期氧疗的较好选择。声门上喷射氧合通气（SJOV）是HFNO的一种有前途的替代方法，具有潜在的益处。
OBJECTIVE: Hypoxia is one of the primary causes that leads to multiple organ injuries and death in COVID-19 patients. Aggressive oxygen therapy for the treatment of hypoxia is important in saving these patients. We have summarized the mechanisms, efficacy, and side effects of various oxygen therapy techniques and their status or the potential to treat hypoxia in COVID-19 patients. The benefit to risk ratio of each oxygen therapy technique and strategy to use them in COVID-19 patients are discussed. High flow nasal cannula oxygen (HFNO) should be considered a better choice as an early stage oxygen therapy. Supraglottic jet oxygenation and ventilation (SJOV) is a promising alternative for HFNO with potential benefits.