VITAMIN-B12 DEFICIENCY IN A BREAST FED INFANT

VITAMIN-B12 DEFICIENCY IN A BREAST FED INFANT
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DOI:
10.1136/adc.63.8.921
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发表时间:
1988-08-01
影响因子:
5.2
通讯作者:
BEARE, T
BEARE, T
中科院分区:
医学2区
文献类型:
--
作者:
MCPHEE, AJ;DAVIDSON, GP;BEARE, T

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我们报告一例5个月大的母乳喂养婴儿病例,该婴儿有呕吐、面色苍白和发育不良的病史。检查显示严重的营养性维生素B12缺乏,并伴有巨幼细胞性全血细胞减少症。这种缺乏是由于母乳中维生素B12浓度低,随后的检查显示母亲患有恶性贫血。对婴儿使用维生素B12治疗后,临床和血液学指标迅速改善。此病例代表了恶性贫血的一种不寻常表现。
We report the case of a 5 month old breast fed infant who presented with a history of vomiting, pallor, and failure to thrive. Investigations showed severe nutritional vitamin B12 deficiency with a megaloblastic pancytopenia. This deficiency was due to low vitamin B12 concentrations in the maternal breast milk, and subsequent investigations showed maternal pernicious anaemia. Treatment of the infant with vitamin B12 resulted in a rapid clinical and haematological improvement. This case represents an unusual presentation of pernicious anaemia.