Assessment of mercury exposure and malaria in a Brazilian Amazon riverine community

Assessment of mercury exposure and malaria in a Brazilian Amazon riverine community
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DOI:
10.1006/enrs.2002.4358
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发表时间:
2002-10-01
影响因子:
8.3
通讯作者:
Silbergeld, E
Silbergeld, E
中科院分区:
环境科学与生态学2区
文献类型:
--
作者:
Crompton, P;Ventura, AM;Silbergeld, E

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巴西亚马逊地区的小规模金矿开采发生在疟疾传播率高的地区。亚马逊人口可能通过直接接触采矿过程和/或食用鱼类而接触到汞。由于实验研究的数据,我们研究了汞影响宿主对疟疾反应的可能性。在帕拉州的一个河流社区Jacareacanga进行了一项横断面调查,该社区位于一个密集的砂金开采区。通过整群抽样从约2000人的总人口中选出205人的样本。进行了简短的病史和检查,获得了疟疾切片,并采集了头发样本以测量汞水平。平均头发汞含量为8.6微克/克,范围为0.3至83.2微克/克。汞含量升高的最重要预测因素是高鱼类消费和低收入。虽然没有流行的疟疾,但报告过去疟疾感染的几率是那些报告有汞工作史的人的四倍。(C)2002 Elsevier Science(美国)。
Small-scale gold mining in the Brazilian Amazon occurs in areas with high rates of malaria transmission. Amazonian populations can be exposed to mercury through direct contact with the mining process and/or through fish consumption. Because of data from experimental studies, we examined the potential for mercury to affect host response to malaria. A cross-sectional survey was done in Jacareacanga, a riverine community in Para state, in a region of intense alluvial gold mining. A sample of 205 persons was selected by cluster sampling from the total population of approximately 2000. A brief medical history and exam were conducted, malaria slides were obtained, and hair samples were taken to measure mercury levels. The average hair mercury level was 8.6 mug/g, ranging from 0.3 to 83.2 mug/g. The most important predictors of elevated mercury levels were high fish consumption and low income. Although there was no prevalent malaria, the odds of reporting a past malaria infection was four times higher for those also reporting a history of working with mercury. (C) 2002 Elsevier Science (USA).