Levels of Severity of Depressive Symptoms Among At-Risk Groups in the UK During the COVID-19 Pandemic.
Levels of Severity of Depressive Symptoms Among At-Risk Groups in the UK During the COVID-19 Pandemic.
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19009年大流行期间，英国高风险群体中抑郁症状的严重程度水平。
DOI：
10.1001/jamanetworkopen.2020.26064
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发表时间：
2020-10-01
影响因子：
13.8
通讯作者：
Fancourt D
中科院分区：
文献类型：
--
作者：
Iob E;Frank P;Steptoe A;Fancourt D
英国 COVID-19 大流行期间，社会人口统计、社会心理和健康相关因素是否与心理健康状况不佳的风险相关？这项队列研究使用了一项包含 51-417 名成年人的大型小组研究数据，发现在遭受虐待或社会支持较低的人、社会经济地位较低的人以及先前存在精神和身体健康状况的人中，中度和重度抑郁症状轨迹的风险显着较高。这些发现表明，当前或未来流行病中的心理健康和社会经济干预措施应针对具有这些危险因素的人。这项队列研究调查了英国 COVID-19 大流行期间高危人群抑郁症状的严重程度。当前的研究重点是调查和监测 2019 年冠状病毒病 (COVID-19) 大流行期间高危人群的心理健康状况。旨在检查 COVID-19 大流行期间英国高危人群抑郁症状随时间的严重程度。这项队列研究是一项针对居住在英国的 18 岁及以上成年人正在进行的大型小组研究（即 COVID-19 社会研究）的一部分，该研究于 2020 年 3 月 21 日成立。数据分析于 2020 年 5 月进行。社会人口学风险因素包括属于黑人、亚裔和少数种族/族裔社区、社会经济地位 (SEP) 较低以及重要的工人角色（例如，卫生和社会护理、教育、儿童保育或关键公共服务领域的工人）。与健康相关和社会心理的危险因素包括先前存在的身心健康状况、心理或身体虐待经历以及社会支持度低。 2020 年 3 月 21 日至 4 月 2 日期间，使用 9 项患者健康问卷 (PHQ-9) 测量了 7 次抑郁症状。使用潜在生长混合模型得出基于群体的抑郁症状轨迹。分析样本包括 51 417 名 18 岁及以上成年人（平均 [SD] 年龄，48.8 [16.8] 岁；26 276 [51.1%] 女性；6145 名黑人、亚洲人和少数种族/族裔社区成员 [12.0%]）。其中，17 143 名参与者 (33.3%) 处于最低 SEP 四分位，11 342 名参与者 (22.1%) 被归类为基本工人。抑郁症状的严重程度分为三个级别：低（30 850 名参与者 [60.0%]）、中度（14 911 名参与者 [29.0%]）和重度（5656 名参与者 [11.0%]）。调整协变量后，身体或心理虐待经历（比值比 [OR]，13.16；95% CI，12.95-13.37；P < .001）、先前存在的心理健康状况（OR，12.99；95% CI，12.87-13.11；P < .001）、先前存在的身体状况健康状况（OR，3.41；95% CI，3.29-3.54；P < .001）、低社会支持（OR，12.72；95% CI，12.57-12.86；P < .001）和低 SEP（OR，5.22；95% CI，5.08-5.36；P < .001）。 P < .001）与严重抑郁症状显着相关。未发现种族/民族之间存在显着关联（OR，1.07；95% CI，0.85-1.28；P = .56）。担任重要工作人员角色的参与者出现严重抑郁症状的可能性较小（OR，0.66；95% CI，0.53-0.80；P < .001）。在具有中度抑郁症状的参与者组中也发现了类似的关联模式（虐待：OR，5.34；95% CI，5.15-5.54；P < .001；心理健康状况：OR，4.24；95% CI，4.24-4.24；P < .001；身体健康状况：OR，1.89；95% CI，1.80-1.98；低社会支持：OR，4.71；95% CI，4.60-4.82；低 SEP：OR，1.87-2.08；在这项针对参与 COVID-19 社会研究的英国成年人的队列研究中，具有心理社会和健康相关风险因素的人以及 SEP 较低的人在 COVID-19 大流行期间最有可能出现中度或重度抑郁症状。
Are sociodemographic, psychosocial, and health-related factors associated with risk of poor mental health during the COVID-19 pandemic in the UK? This cohort study using data from a large panel study including 51 417 adults found that the risks of moderate and severe depressive symptom trajectories were significantly higher among people experiencing abuse or low social support, individuals with low socioeconomic position, and those with preexisting mental and physical health conditions. These findings suggest that mental health and socioeconomic interventions in the current or future pandemics should be targeted toward people with these risk factors. This cohort study examines the levels of severity of depressive symptoms among at-risk individuals during the COVID-19 pandemic in the UK. An immediate research priority is to investigate and monitor the psychological well-being among high-risk groups during the coronavirus disease 2019 (COVID-19) pandemic. To examine levels of severity of depressive symptoms over time among individuals with high risk in the UK during the COVID-19 pandemic. This cohort study is part of an ongoing large panel study of adults aged 18 years and older residing in the UK, the COVID-19 Social Study, established on March 21, 2020. Data analysis was conducted in May 2020. Sociodemographic risk factors included belonging to the Black, Asian, and minority racial/ethnic communities, low socioeconomic position (SEP), and essential worker roles (eg, workers in health and social care, education, childcare, or key public services). Health-related and psychosocial risk factors included preexisting physical and mental health conditions, experience of psychological or physical abuse, and low social support. Depressive symptoms were measured on 7 occasions from March 21 to April 2, 2020, using the 9-item Patient Health Questionnaire (PHQ-9). Group-based depressive symptom trajectories were derived using latent growth mixture modeling. The analytical sample comprised 51 417 adults aged 18 years and older (mean [SD] age, 48.8 [16.8] years; 26 276 [51.1%] women; 6145 members [12.0%] of Black, Asian, and minority racial/ethnic communities). Among these, 17 143 participants (33.3%) were in the lowest SEP quartile, and 11 342 participants (22.1%) were classified as essential workers. Three levels of severity of depressive symptoms were identified: low (30 850 participants [60.0%]), moderate (14 911 participants [29.0%]), and severe (5656 participants [11.0%]). After adjusting for covariates, experiences of physical or psychological abuse (odds ratio [OR], 13.16; 95% CI, 12.95-13.37; P < .001), preexisting mental health conditions (OR, 12.99; 95% CI, 12.87-13.11; P < .001), preexisting physical health conditions (OR, 3.41; 95% CI, 3.29-3.54; P < .001), low social support (OR, 12.72; 95% CI, 12.57-12.86; P < .001), and low SEP (OR, 5.22; 95% CI, 5.08-5.36; P < .001) were significantly associated with severe depressive symptoms. No significant association was found for race/ethnicity (OR, 1.07; 95% CI, 0.85-1.28; P = .56). Participants with essential worker roles were less likely to experience severe depressive symptoms (OR, 0.66; 95% CI, 0.53-0.80; P < .001). Similar patterns of associations were found for the group of participants with moderate depressive symptoms (abuse: OR, 5.34; 95% CI, 5.15-5.54; P < .001; mental health condition: OR, 4.24; 95% CI, 4.24-4.24; P < .001; physical health condition: OR, 1.89; 95% CI, 1.80-1.98; P < .001; low social support: OR, 4.71; 95% CI, 4.60-4.82; P < .001; low SEP: OR, 1.97; 95% CI, 1.87-2.08; P < .001). In this cohort study of UK adults participating in the COVID-19 Social Study, people with psychosocial and health-related risk factors, as well as those with low SEP, were at the most risk of experiencing moderate or severe depressive symptoms during the COVID-19 pandemic.
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影响因子：
0.5
作者：
Kroenke, K;Spitzer, RL
通讯作者：
Spitzer, RL
影响因子：
14.6
作者：
Nickell, LA;Crighton, EJ;Upshur, REG
通讯作者：
Upshur, REG
影响因子：
25.8
作者：
Scott KM;Lim C;Al-Hamzawi A;Alonso J;Bruffaerts R;Caldas-de-Almeida JM;Florescu S;de Girolamo G;Hu C;de Jonge P;Kawakami N;Medina-Mora ME;Moskalewicz J;Navarro-Mateu F;O'Neill S;Piazza M;Posada-Villa J;Torres Y;Kessler RC
通讯作者：
Kessler RC
DOI：
10.1016/s2468-2667(17)30075-0
发表时间：
2017-06
期刊：
The Lancet. Public health
影响因子：
--
作者：
Elovainio M;Hakulinen C;Pulkki-Råback L;Virtanen M;Josefsson K;Jokela M;Vahtera J;Kivimäki M
通讯作者：
Kivimäki M
影响因子：
3.6
作者：
Krebber, A. M. H.;Buffart, L. M.;Kleijn, G.;Riepma, I. C.;de Bree, R.;Leemans, C. R.;Becker, A.;Brug, J.;van Straten, A.;Cuijpers, P.;Verdonck-de Leeuw, I. M.
通讯作者：
Verdonck-de Leeuw, I. M.