Morphology Variability Analysis of Wrist Pulse Waveform for Assessment of Arteriosclerosis Status
Morphology Variability Analysis of Wrist Pulse Waveform for Assessment of Arteriosclerosis Status
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DOI：
10.1007/s10916-008-9245-6
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发表时间：
2010-06-01
影响因子：
5.3
通讯作者：
Wang, Kuanquan
中科院分区：
文献类型：
--
作者：
Xu, Lisheng;Meng, Max Q. -H.;Wang, Kuanquan
本文应用近似熵（ApEn）研究脉搏波波形的变异性，以评价冠状动脉粥样硬化状态。通过对正常人和冠状动脉粥样硬化（CA）患者腕部脉搏波形的分析，发现脉搏形态变异性（PMV）比脉搏间期变异性（PIV）更能有效地评价冠状动脉的状态。通常，健康人的PMV高于CA疾病患者的PMV，并且CA疾病患者的PMV比健康受试者的PMV具有更多的高频成分。也就是说，CA疾病对血管张力也有影响。由于CA疾病引起的心脏性能变化的影响可以通过PMV反映出来。实验表明，PMV谱能量比对心血管系统临床诊断的特异性和敏感性分别为80%和97%。
In this paper, approximate entropy (ApEn) is applied to study the variability of pulse waveform for assessing coronary arteriosclerosis status. Having analyzed the wrist pulse waveforms taken from both normal subjects and the patients suffering from coronary arteriosclerosis (CA) disorders, we find that pulse morphology variability (PMV) is more efficient than pulse interval variability (PIV) in assessing the conditions of human coronary artery. Usually, the PMVs of the healthy are higher than those of the patients with CA diseases, and the PMVs of patients with CA diseases have more high frequency components than those of the healthy subjects. That is to say, the CA disease also has influence on vascular tone. The effect of changes in cardiac performance due to CA disease can be reflected through the PMV. The experiment demonstrates that the specificity and sensitivity of the PMV's spectral energy ratio for clinical diagnosis of cardiovascular system is 80% and 97%, respectively.