Exposure to paternal tobacco smoking increased child hospitalization for lower respiratory infections but not for other diseases in Vietnam.
Exposure to paternal tobacco smoking increased child hospitalization for lower respiratory infections but not for other diseases in Vietnam.
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DOI：
10.1038/srep45481
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发表时间：
2017-03-31
影响因子：
4.6
通讯作者：
Yasunami M
中科院分区：
文献类型：
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作者：
Miyahara R;Takahashi K;Anh NT;Thiem VD;Suzuki M;Yoshino H;Tho LH;Moriuchi H;Cox SE;Yoshida LM;Anh DD;Ariyoshi K;Yasunami M
暴露于环境烟草烟雾（ETS）是儿童住院的一个重要的可改变的风险因素，尽管在母亲吸烟导致的ETS可以忽略不计的国家，其贡献没有得到很好的记录。我们在2009年5月至2010年5月期间在越南芽庄对1999名新生儿进行了一项出生队列研究，以评估父亲吸烟作为感染性和非感染性疾病的危险因素。使用医院记录确定24个月观察期内的住院情况。使用Poisson回归模型评估了妊娠期和婴儿期父亲暴露对传染病发病率的影响。总共有35.6%的1624名参加随访的儿童在2岁时至少需要住院一次，最常见的住院原因是下呼吸道感染（LRTI）。在调整可能的混杂因素后，父亲吸烟独立地增加了LRTI的风险1.76倍（95%CI：1.24-2.51），但与任何其他住院原因无关。人群归因分数表明，在这种流行病学背景下，有效的干预措施，以防止父亲吸烟的儿童将减少14.8%的LRTI相关的住院治疗。
Exposure to environmental tobacco smoke (ETS) is an important modifiable risk factor for child hospitalization, although its contribution is not well documented in countries where ETS due to maternal tobacco smoking is negligible. We conducted a birth cohort study of 1999 neonates between May 2009 and May 2010 in Nha Trang, Vietnam, to evaluate paternal tobacco smoking as a risk factor for infectious and non-infectious diseases. Hospitalizations during a 24-month observation period were identified using hospital records. The effect of paternal exposure during pregnancy and infancy on infectious disease incidence was evaluated using Poisson regression models. In total, 35.6% of 1624 children who attended follow-up visits required at least one hospitalization by 2 years of age, and the most common reason for hospitalization was lower respiratory tract infection (LRTI). Paternal tobacco smoking independently increased the risk of LRTI 1.76-fold (95% CI: 1.24–2.51) after adjusting for possible confounders but was not associated with any other cause of hospitalization. The population attributable fraction indicated that effective interventions to prevent paternal smoking in the presence of children would reduce LRTI-related hospitalizations by 14.8% in this epidemiological setting.